Metrogyl Compound Plus Tablet

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Metrogyl Compound Plus Tablet 10’S


Metrogyl Compound Plus Tablet

Metrogyl Compound Plus Tablet is a combination medicine used in the treatment of diarrhea. It kills diarrhea-causing bacteria. It also manages the symptoms of diarrhea such as stomach pain, cramps, loose stools and helps in easy passage of gas.

Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends.

If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, vomiting, taste change, flatulence, and headache. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects.

This medicine may also cause dizziness and drowsiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have kidney diseases so that your doctor can prescribe a suitable dose for you.

Metrogyl Compound Plus, a prescription drug, is manufactured in various forms such as Tablet. It is primarily used for the treatment of Amebiasis, Flatulence, Amebiasis. The alternative uses of tablet have also been explained below.

The correct dosage of tablet depends on the patient’s age, gender, and medical history. Individual symptoms and route of administration also determines the right dosage. For detailed information on this, read through the dosage section.

The side effects typically associated with Metrogyl Compound Plus include Flatulence, Nausea or vomiting, Itching or burning. Besides the aforementioned side effects, there are other adverse effects of tablet as well, which are listed below.

Usually, these side effects of tablet go away soon, and do not persist beyond the duration of the treatment. If, however, they worsen or do not go away, please speak with your physician.

Furthermore, you should know that effect of Metrogyl Compound Plus is Moderate for pregnant women and Moderate for women who are breastfeeding.

It is important to know if Metrogyl Compound Plus has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Metrogyl Compound Plus related warnings section.

Metrogyl Compound Plus can cause adverse effects in certain medical conditions. It is strongly recommended to avoid tablet in conditions like Peripheral Neuropathy. Other contraindications of tablet have been discussed in the sections ahead.

Besides this, Metrogyl Compound Plus may also have severe interaction with some medicines. A complete list of these interactions is given below.

Along with the above-mentioned precautions, remember that taking Metrogyl Compound Plus is considered not safe while driving, and is not addictive. Read more: Metrogyl Compound Plus


  • Diarrhea


In Diarrhea

Diarrhea is an increase in the frequency of bowel movements or loose watery bowel movements. It can most commonly occur due to an infection of the digestive tract. Metrogyl Compound Plus Tablet helps to treat diarrhea that is caused due to bacteria or parasitic worm infections.
This medicine can relieve frequent loose motions and also help you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.


Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Metrogyl Compound Plus

  • Nausea
  • Vomiting
  • Taste change
  • Flatulence
  • Sleepiness
  • Headache
  • Dizziness


Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metrogyl Compound Plus Tablet may be taken with or without food, but it is better to take it at a fixed time.


Metrogyl Compound Plus Tablet is a combination of three medicines: Diloxanide, ornidazole and simethicone. Diloxanide is a luminal amoebicide which acts inside the intestines to kill the infection-causing microorganisms (amoeba). Diloxanide is combined with ornidazole in case of severe intestinal infections.
Ornidazole is an antibiotic which kills bacteria and other infectious microorganisms by damaging the DNA. Simethicone is an antifoaming medicine which disintegrates gas bubbles and allows easy passage of gas.

Metrogyl Compound Plus Tablet, an antiprotozoal agent, is the most effective medicine for the patients suffering from amoeba infections (mainly caused by Entamoeba histolytica). As far as health issues are concerned, this is one of the safest medicines.

Recommended dosage is 500mg three times a day for 10 days and the course may be repeated if needed. However excess dosage should be avoided.

The mechanism of action of this medicine is, however, unknown. But, as it is a luminal amoebicide it is assumed to work by destroying the trophozoites of Entamoeba histolytica which then form into cysts and the cysts are then excreted out of the body.

The structure of this medication can be related to chloramphenicol as it acts by blocking protein synthesis. The furoate salt of this drug behaves as a prodrug which is metabolized in the gastrointestinal tract to produce diloxanide, the active drug. About 90% of each dose is excreted by urine and the rest through feces.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.




It is unsafe to consume alcohol with Metrogyl Compound Plus Tablet.


Metrogyl Compound Plus Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

Information regarding the use of Tablet during breastfeeding is not available. Please consult your doctor.


Tablet may cause side effects which could affect your ability to drive.


Metrogyl Compound Plus Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Tablet may not be needed in these patients. Please consult your doctor.


Metrogyl Compound Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Tablet may be needed. Please consult your doctor.


If you miss a dose of Metrogyl Compound Plus Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Q. What if I miss my dose?

Take Metrogyl Compound Plus Tablet as soon as you remember it. However, do not take it if it’s almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.

Q. Can I stop taking Metrogyl Compound Plus Tablet when I feel better?

No, do not stop taking Metrogyl Compound Plus Tablet and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

Q. What if I don’t get better after using Metrogyl Compound Plus Tablet?

Inform your doctor if you don’t feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
Ques: What is Metrogyl Compound Plus Tablet?
Ans: This medication an antiprotozoal agent, is the most effective medicine and very much safe as far as health issue is concerned
Ques: How long do I need to use Metrogyl Compound Plus Tablet before I see improvement in my condition?
Ans: This medication is to be taken till the time you see an improvement in your health conditions.
Ques: At what frequency do I need to use Metrogyl Compound Plus Tablet?
Ans: The recommended dosage is 500 mg three times a day for 10 days and the course may be repeated if needed.
Ques: Should I use Metrogyl Compound Plus Tablet empty stomach, before food or after food?
Ans: This medication should be taken after food in a prescribed dosage.
Ques: What are the instructions for the storage and disposal of Metrogyl Compound Plus Tablet?
Ans: This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.


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Metrogyl Compound Plus Tablet 10’S

Metrogyl Compound Plus Tablet