Xarelto 10 Mg Tablet

XARELTO 10MG contains rivaroxaban which belongs to the group of medicines called anticoagulants. A blood clot which blocks an artery (blood vessel) is called an embolism and if the embolism occurs in the arteries of the brain it can cause a stroke. Anticoagulants slow down the time it takes for blood to clot and reduce the risk of embolism.

This medicine is used in the treatment and prevention of deep vein thrombosis (blood clots in veins of legs) and pulmonary embolism (blood clot in lungs) in patients with or without hip or knee replacement operation. It also prevents the formation of blood clots in your brain (stroke) and other blood vessels of body among patients with non-valvular atrial fibrillation (an abnormal heartbeat).

Rivaroxaban acts by blocking the activity of blood clotting factor (factor Xa) and reduces the tendency of the blood to form clots. This medicine must be taken only with meals. The most common side effects of taking this medicine are bleeding in eyes, nose, gums, stomach, rectum or vagina. Do not take this medicine, if you have any bleeding disorders. Before taking this medicine inform your doctor if you are pregnant, breastfeeding or having any serious kidney or liver disease. This medicine is not recommended for use in children and adolescents under 18 years of age.

USES OF XARELTO 10MG:

Treats and prevents deep vein thrombosis
Treats and prevents pulmonary embolism in patients with or without hip or knee replacement operation
Prevents stroke and formation of blood clots in other blood vessels of body among patients with non-valvular atrial fibrillation (an abnormal heartbeat)

HOW XARELTO 10MG WORKS:

XARELTO 10MG reversibly inhibits both the free- and clot-bound forms of coagulation factor Xa. Inhibition of Xa, prevents the conversion of prothrombin into thrombin, which activates platelets and catalyzes the conversion of fibrinogen to fibrin thread (clot) and thus prevents blood clot formation.

DIRECTIONS FOR USE:

Take this medicine as directed by your physician. It must be taken only with meals. Your doctor will decide the correct dose for you depending upon your condition. Swallow the medicine as whole with a glass of water. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF XARELTO 10MG:

SERIOUS

Long or excessive bleeding
Skin reactions (such as skin rash, blisters or mucosal lesions, swelling of face, lips, mouth, tongue or throat, difficulty in swallowing or breathing, drop in blood pressure)
DRESS syndrome (fever, rash, inflammation of internal organs, hematologic abnormalities and systemic illness)

COMMON

Bleeding disorders
Bruising and swelling
Anemia, tiredness or paleness
Coughing up blood
Pain and swelling in the limbs
Fever
Stomach pain, indigestion
Nausea (feeling sick) or vomiting (being sick)
Constipation, diarrhea
Low blood pressure
Headache, dizziness
Skin rash

RARE

Bleeding into a muscle
Yellowing of skin and eye (jaundice)

HOW TO MANAGE SIDE EFFECTS:

Nausea or vomiting:

Try taking this medicine with, or just after meal. Stick to simple meals. Do not eat rich or spicy food.

Constipation:

Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.

Diarrhea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

WARNING & PRECAUTION:

PREGNANCY

XARELTO 10MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

XARELTO 10MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or operate any machines if your ability is affected by this medicine.

ALCOHOL

Avoid consumption of alcohol while taking this medicine.

KIDNEY

XARELTO 10MG should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.

LIVER

Do not take XARELTO 10MG if you have a liver disease which leads to increased risk of bleeding (hepatic coagulopathy). Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic (hypersensitive) to rivaroxaban.

LUNGS

XARELTO 10MG should be taken with caution in patients with previous bleeding from lung or bronchiectasis (bronchi are widened and filled with pus). Consult your doctor for advice.

HEART DISEASE

XARELTO 10MG should be taken with caution in patients with prosthetic heart valve. Consult your doctor for advice.

OTHERS

Inform your doctor before taking this medicine, if you have:

Any bleeding disorders

INTERACTIONS:

Talk to your doctor, if you are taking,

Medicines used to treat fungal infections (e.g., ketoconazole, itraconazole, voriconazole, posaconazole)
Medicines used to treat HIV infections (e.g., ritonavir)
Medicines used to treat bacterial infection (e.g. clarithromycin, erythromycin)
Other medicines used to reduce blood clotting (e.g., enoxaparin, warfarin, rivaroxaban, dabigatran or heparin)
Medicines used to reduce pain or inflammation (e.g., acetylsalicylic acid or naproxen)
Medicines used to treat depression (e.g. fluoxetine, sertraline, imipramine, St John?s Wort)
Medicines used to treat epilepsy (e.g., phenytoin, carbamazepine, phenobarbital)
Dronedarone (used to treat abnormal heartbeat)
Rifampicin (used to treat tuberculosis)

SYNOPSIS:

Drug : Rivaroxaban
Pharmacological Category : Anticoagulant
Therapeutic Indication : Blood clot
Dosage Forms : Tablet

MORE INFORMATION:

Store at room temperature and keep out of reach of children.

FAQ’s ABOUT XARELTO 10MG:

Q: Can you drink alcohol while taking XARELTO 10MG?
A: No. Avoid consumption of alcohol while taking this medicine, as it may make you feel dizzier.

Q: Can you take ibuprofen with XARELTO 10MG?
A: No. Avoid concomitant use of this medicine with ibuprofen or any other pain killers without consulting your doctor.

SAFETY ADVICE

Alcohol

Caution is advised when consuming alcohol with Xarelto 10mg Tablet. Please consult your doctor.

Pregnancy

Xarelto 10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

Xarelto 10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

Xarelto 10mg Tablet may cause side effects which could affect your ability to drive.
Xarelto 10mg Tablet may cause dizziness or fainting. This may affect your driving ability.

Kidney

Xarelto 10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Xarelto 10mg Tablet may be needed. Please consult your doctor.
Use of Xarelto 10mg Tablet is not recommended in patients with severe kidney disease.

Liver

Xarelto 10mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.