DANOGEN 50MG contains Danazol which is in a class of medications called androgenic hormones. It used to treat endometriosis (where the tissue that normally lines your womb and is shed during your period grows outside your womb). You may be given Danazol before or after surgery for the endometriosis. Danazol is a synthetic androgen. Androgens are hormones produced by the male testes. They are responsible for the functioning of the male reproductive system and the development of the male characteristics, such as facial hair and a deep voice. The ovaries also produce small amounts of androgens.
Always take DANOGEN 50MG exactly as prescribed by your doctor. Do not split, chew, or crush this medicine. Swallow the medicine whole, with water. It helps in the treatment of the endometriosis and has same effectiveness as the other hormonal treatments. However, it has androgenic (male-like) side effects, including weight gain, increased body hair and acne. Its unpleasant side effects and its tendency to adversely affect blood lipid (cholesterol) levels mean it is not usually the first choice of treatment for endometriosis.
USES OF DANOGEN 50MG
- Endometriosis (where the tissue that normally lines your womb and is shed during your period grows outside your womb)
- Painful or heavy periods (menorrhagia)
- Painful breast disease but not malignant
- Enlarged breasts (in both men and women)
HOW DANOGEN 50MG WORKS
DANOGEN 50MG does not cure endometriosis permanently. Rather, it suppresses its growth and development temporarily, so the disease may recur following treatment. It has a multiple effect on the body. Some of these effects combine to produce high levels of androgen and low levels of oestrogen in the body. This hormonal environment stops menstruation and suppresses the growth of endometrial implants, causing them to degenerate.
Most women will stop ovulating and menstruating by the second month of treatment, though this may depend on the dosage used. The symptoms of endometriosis usually begin to diminish by the end of the second month. Most women will resume ovulating and menstruating within 46 weeks of stopping treatment.
DIRECTIONS FOR USE
Always take DANOGEN 50MG exactly as prescribed by your doctor. Do not split, chew, or crush this medicine. Swallow the medicine whole, with water.
SIDE EFFECTS OF DANOGEN 50MG
SERIOUS
- Allergic reaction (skin rash, swelling of the face, lips, tongue or throat, swallowing or breathing problems)
- Pain or tightness in the chest or arm. These could be signs of a heart attack
COMMON
- Headache
- Blurred vision
- Diarrhea
- Hair loss
- Skin rash
- Dizziness
- Nausea, vomiting
- Stomach pain
- Weight gain
- Changes in sex drive (libido)
- Increased appetite, anxiety, nervousness, depression
- Breathlessness, swelling or inflammation of the lungs (interstitial pneumonitis)
RARE
- Sensitivity of the skin to sunlight
- Changes in the number of red blood cells or platelets in your blood. You may also notice that you bruise or bleed easily or unexpectedly
- Increase in certain types of the white blood cells
- Raised levels of an enzyme (creatine phosphokinase)
- Changes in the level of fat (lipid) in your blood
HOW TO MANAGE SIDE EFFECTS
Nausea and vomiting:
Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Headache:
Rest and drink plenty of fluids. Apply a cold, wet cloth or ice pack to your forehead. Rest in a quiet, comfortable, dark room.
Skin rash:
Avoid hot showers or baths because hot water can irritate the skin. Moisturizers can be used regular basis to soothe and hydrate the affected area.
Stomach pain:
Try to rest and relax. You can eat and drink slowly or have frequent meals. Keeping a heat pad or a covered hot water pack on your stomach may also help. If still pain persists, speak to your doctor.
SAFETY ADVICE
Alcohol
Pregnancy
Breast feeding
Driving
Danogen 50 Capsule may cause some side effects such as dizziness, a spinning feeling, and changes in eyesight. This may affect your driving ability.
Kidney
Use of Danogen 50 Capsule may not be advised in patients with severe kidney disease.
Liver
Use of Danogen 50 Capsule is not recommended in patients with the severe liver disease. Regular monitoring of liver function tests is advised while you are taking this medicine.
INTERACTIONS
Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:
- Medicines for epilepsy, fits or convulsions (anticonvulsants)
- Medicines used to thin the blood (warfarin)
- Steroids such as testosterone, estrogen, progesterone (including the Pill or hormone replacement therapy known as HRT)
- Statins such as simvastatin. It may increase the risk of muscle weakness or rapid breakdown of muscle
MORE INFORMATION
Store below 20-25°C and keep out of reach of children.
FAQs ABOUT DANOGEN 50MG
Q: What is DANOGEN 50MG used for in men?
A: It is used in both men and women to prevent attacks of angioedema of all types (cutaneous, abdominal, laryngeal).
Q: Is DANOGEN 50MG a steroid?
A: It is a synthetic steroid used to treat pelvic pain and infertility due to endometriosis and also to treat breast pain/tenderness/nodules due to fibrocystic breast disease.
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