PTH 30mg Tablet

PTH 30MG contains cinacalcet which belongs to a group of medicines called calcimimetic agent that increases the sensitivity of the calcium-sensing receptor to activation by extracellular calcium. It treats problem with the organs called parathyroid glands. The parathyroids are four small glands in the neck, near thyroid gland, that produce the parathyroid hormone (PTH). Hyperparathyroidism (HPT) is a condition where the parathyroid gland may become overactive and make too much PTH. In this condition the calcium stored in the bones move into the blood leading to hypercalcemia (too much calcium in the blood).

Secondary hyperparathyroidism (SHPT) describes an alteration in bone and mineral metabolism that occurs as a direct result of chronic kidney disease (CKD). The parathyroid gland is the central organ responsible for regulating these adaptive responses leading to secondary hyperparathyroidism. Parathyroid hormone helps prevent low calcium levels by acting on the bones, intestine, and kidneys. PTH 30MG works by controlling levels of the parathyroid hormone (PTH), calcium and phosphorous in body.

Children under the age 18 with parathyroid cancer or primary hyperparathyroidism must not take this medicine. Do not drive or operate machines, if you experience side effects such as dizziness and seizures. If you are pregnant or breast-feeding, think you may be pregnant or planning to have a baby, ask your doctor for advice before taking this medicine. The usual starting dose for this medicine in adults is 30 mg twice per day or as directed by your physician. Swallow the medicine whole with plenty of water. The most common side effects are nausea, vomiting, dizziness, rash, muscle pain, loss of appetite, headache, etc.

USES OF PTH 30MG:

Secondary hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) on dialysis
Hypercalcemia in patients with Parathyroid carcinoma and primary hyperparathyroidism (HPT)

HOW PTH 30MG WORKS:

PTH 30MG works by controlling levels of the parathyroid hormone (PTH), calcium and phosphorous in body.

DIRECTIONS FOR USE:

The usual starting dose for this medicine in adults is 30 mg twice per day or as prescribed by your doctor. Swallow the medicine whole with plenty of water.

SIDE EFFECTS OF PTH 30MG:

SERIOUS

Numbness or tingling around mouth, muscle aches or cramps and seizures. These may be signs of low calcium levels (hypocalcaemia)
Swelling of face, lips, mouth, tongue or throat which may cause by difficulty in swallowing or breathing (angioedema)

COMMON

Dizziness, headache
Nausea or vomiting
Constipation
Feeling weak
Loss (anorexia) or decrease of appetite
Muscle pain (myalgia)
Weakness (asthenia)
Rash
Reduced testosterone levels
High potassium levels in the blood (hyperkalaemia)
Allergic reactions (hypersensitivity)
Diarrhea
Indigestion

HOW TO MANAGE SIDE EFFECTS:

Constipation:

Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

Nausea and vomiting:

Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

INTERACTIONS:

Talk to your doctor if you are taking medicines used to:

Treat the skin and fungal infections
Treat the bacterial infections (telithromycin, rifampicin and ciprofloxacin)
Treat HIV infection and AIDS (ritonavir)
Treat depression (fluvoxamine)
Treat depression
Relieve cough (dextromethorphan)
Treat the changes in heart rate (flecainide and propafenone)
Treat high blood pressure

SYNOPSIS:

Drug : Cinacalcet
Pharmacological Category : Calcimimetics
Therapeutic Indication : Hyperparathyroidism
Dosage Forms : Tablet

MORE INFORMATION:

Store below 20-25°C and keep out of reach of children.

PRODUCT INTRODUCTION

USES OF PTH TABLET

• Treatment of High calcium levels in the blood
• Treatment of Hyperparathyroidism

BENEFITS OF PTH TABLET

In Treatment of High calcium levels in the blood

Calcium is a mineral found in different places in your body and has many functions including bone growth. Most of your calcium should be in your bones. When you have more calcium in your blood than normal it is called hypercalcemia. Pth 30 Tablet reduces the amount of calcium in your blood.

Being immobile makes hypercalcemia worse. Whenever possible you should take regular exercise, especially weight-bearing exercise. Do not take calcium or vitamin D3 supplements and try to decrease your intake of these in your diet.

In Treatment of Hyperparathyroidism

Hyperparathyroidism is a condition in which the parathyroid glands become overactive and secrete too much parathyroid hormone. This leads to high levels of calcium in our blood, a condition called hypercalcemia. Pth 30 Tablet helps reduce this increased secretion of parathyroid hormone and restores the calcium levels to normal. It helps prevent complications of hypercalcemia such as osteoporosis (a bone disorder), frequent fracture, reduced height, kidney stones etc.

SIDE EFFECTS OF PTH TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pth

• Vomiting
• Nausea
• Rash
• Headache
• Muscle pain
• Diarrhea

HOW TO USE PTH TABLET

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pth 30 Tablet may be taken with or without food, but it is better to take it at a fixed time.

HOW PTH TABLET WORKS

Pth 30 Tablet works by lowering a chemical (parathyroid hormone), which makes calcium level go back to normal.

SAFETY ADVICE

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Pth 30 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Pth 30 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Pth 30 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Pth 30 Tablet may cause side effects which could affect your ability to drive.
Dizziness and seizures have been reported by patients taking Pth 30 Tablet. This may affect your driving ability.

Kidney

SAFE IF PRESCRIBED

Pth 30 Tablet is safe to use in patients with kidney disease. No dose adjustment of Pth 30 Tablet is recommended.

Liver

CAUTION

Pth 30 Tablet should be used with caution in patients with liver disease. Dose adjustment of Pth 30 Tablet may be needed. Please consult your doctor.

FAQs ABOUT PTH 30MG:

Q: Can PTH 30MG be used in pregnant women?
A: No. It is not recommended for use in the pregnant women. Consult your doctor before taking.

Q: Does PTH 30MG cause hypocalcemia?
A: It can cause acute, severe and symptomatic hypocalcaemia in susceptible patients, possibly those with prolonged high bone turnover states or those not receiving VDRA therapy.