XIDORIN Tablet

Xidorin

XIDORIN contains Midodrine which belongs to the group of medicines called alpha-1 adrenergic agonist. It is used to treat low blood pressure in adults when other treatments have not worked. Symptoms of low blood pressure includes dizziness or lightheadedness, fainting, blurred vision, nausea, fatigue or lack of concentration.

Midodrine is a prodrug of deglymidodrine. It increases your blood pressure by enhancing smooth muscle tone leading to vasoconstriction of blood vessels. Prior to the treatment, your doctor would check your kidney function and blood pressure to access your condition. During the treatment, regular monitoring of your blood pressure while you are lying down or standing up will be required.

The most common side effects of taking this medicine are high blood pressure, chest pain, increased heartbeat, shortness of breath, headache and blurred vision. Contact your doctor immediately, if you experience any of these symptoms. It is always important that you do not take this medicine late in the evening. Try to take your last daily dose at least 4 hours before bedtime. Before taking this medicine, inform your doctor if you have any other heart disease or kidney disease. This medicine is not recommended for use in pregnant or breastfeeding women and in children less than 18 years of age.

USES OF XIDORIN

• Treats low blood pressure

HOW XIDORIN WORKS

Midodrine is converted to its active metabolite, deglymidodrine which binds to and activates alpha1-adrenergic receptors present in the blood vessels, which enhances smooth muscle tone, leading to peripheral vasoconstriction and elevation of blood pressure.

DIRECTIONS FOR USE

Take this medicine as directed by your physician. Do not crush or chew the medicine. Your doctor will decide the correct dose for you depending upon your condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF XIDORIN

RARE

• Increased heartbeat

HOW TO MANAGE SIDE EFFECTS

Feeling sick (nausea):

Try taking this medicine with, or just after meal. Stick to simple meals. Do not eat rich or spicy food.

Scalp itching:

Avoid hot showers or baths because hot water can irritate the scalp. Do not rub or scratch the affected area.

Headache:  

Rest and drink plenty of fluids. Do not drink too much alcohol.

INTERACTIONS

Talk to your doctor, if you are taking,

• Other medicines used to reduce high blood pressure (e.g. reserpine and guanethidine)
• Medicines used to treat other heart conditions like heart failure, abnormal heartbeat (e.g. prazosin, phentolamine, digoxin)
• Medicines used to treat allergies (e.g. fluticastone)
• Medicines used to treat thyroid disorders (e.g. levothyroxine)
• Medicines used to treat depression (e.g. fluoxetine, sertraline, amitriptyline)
• Medicines which relieve nasal congestion relievers (e.g. dexamethasone)
• Medicines that narrow blood vessels (e.g. phenylephrine, dopamine)
• Sympathomimetic agents (e.g. ephedrine)
• Steroids (used to treat inflammation) e.g. fludrocortisone acetate

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

PRODUCT INTRODUCTION

Xidorin Tablet is used to treat low blood pressure (hypotension). It is used in patients who experience dizziness due to low blood pressure while standing up suddenly from sitting or lying position. This medicine causes tightening of blood vessels and results in elevating your blood pressure.

Xidorin Tablet can be taken with or without food. This medicine is taken during daytime hours when people stand most often. But, it should not be taken if you are going to lie down for a long time after the dose. You should always take this medicine as advised by the doctor and should never stop it without consulting the doctor. You should monitor your blood pressure regularly while taking this medicine.

Common side effects of this medicine include headache, nausea, rash, and difficulty in urination. Consult your doctor if these side effects bother you. It may also cause supine hypertension, it is increase in your blood pressure while lying down.

Before taking this medicine, it is better to let your doctor know if you are suffering from any kidney or liver disease. Also, pregnant women and breastfeeding mothers should consult doctor before taking it. You must inform doctor about all the other medicines that you are taking apart from this medicine. Your doctor may ask for monitoring of kidney and liver function before and during the treatment with this medicine.

USES OF XIDORIN TABLET

• Low blood pressure

BENEFITS OF XIDORIN TABLET

In Low blood pressure

Xidorin Tablet is used in adults and children to relieve low blood pressure which may occur due to sudden change in posture from lying to sitting or standing up, during an operation or after an injury. This medicine helps to bring back the blood pressure within normal range and therefore prevents any sudden fall or even serious complications that might have otherwise followed due to low blood pressure.

SIDE EFFECTS OF XIDORIN TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Xidorin

• Headache
• Nausea
• Rash
• Difficulty in urination

HOW TO USE XIDORIN TABLET

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xidorin Tablet may be taken with or without food, but it is better to take it at a fixed time.

HOW XIDORIN TABLET WORKS

Xidorin Tablet is an alpha-adrenergic agonist. It works by activating specific receptors on blood vessels. This causes the blood vessels to tighten, which increases blood pressure.

SAFETY ADVICE

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Xidorin Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Xidorin Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Xidorin Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Xidorin Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Xidorin Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Xidorin Tablet in patients with liver disease. Please consult your doctor.

FAQ’s ABOUT XIDORIN

Q: Can XIDORIN cause increase in heart rate?
A: Yes. It may cause increase in heart rate in some individuals. Consult your doctor for advice.

Q: Can XIDORIN be used in children?
A: No. This medicine is not recommended for use in children and adolescents under the age 18.