Larentine 5mg Tablet
LARENTINE 5MG contain memantine which belongs to a group of medicine called NMDA receptor antagonists. It is used for the treatment of patients with moderate to severe Alzheimer’s disease. Alzheimer’s disease is a progressive disease that destroy memory and mental functions.
Memory loss in Alzheimer’s disease is due to disturbance of message signals in the brain. The brain contains N-methyl-D-aspartate (NMDA)-receptor that are involved in transmitting nerve signals important in learning and memory. This medicine acts on these NMDA-receptors improving the transmission of nerve signals and the memory.
Glutamate is a chemical that helps to send messages between nerve cells in the brain. In Alzheimer’s disease nerve cells are damaged resulting in the production of too much of glutamate. This causes more damage to the nerve cells. Memantine protects nerve cells by blocking the effects of excess glutamate without disturbing the normal transmission of nerve signals.
The common side effects are headache, sleepiness, constipation, elevated liver function tests, dizziness, balance disorders, shortness of breath, high blood pressure, hypersensitivity. This medicine is strictly not recommended for use in children and adolescents under 18 years. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.
LARENTINE 5MG contain memantine which belongs to a group of medicine called NMDA receptor antagonists. It is used for the treatment of patients with moderate to severe Alzheimers disease. Alzheimers disease is a progressive disease that destroy memory and mental functions. Memory loss in Alzheimers disease is due to disturbance of message signals in the brain.
The brain contains N-methyl-D-aspartate (NMDA)-receptor that are involved in transmitting nerve signals important in learning and memory. This medicine acts on these NMDA-receptors improving the transmission of nerve signals and the memory.
Glutamate is a chemical that helps to send messages between nerve cells in the brain. In Alzheimers disease nerve cells are damaged resulting in the production of too much of glutamate. This causes more damage to the nerve cells. Memantine protects nerve cells by blocking the effects of excess glutamate without disturbing the normal transmission of nerve signals.
The common side effects are headache, sleepiness, constipation, elevated liver function tests, dizziness, balance disorders, shortness of breath, high blood pressure, hypersensitivity.
This medicine is strictly not recommended for use in children and adolescents under 18 years. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.
Larentine 5 Tablet 10’s belongs to a group of medicines called anti-dementia agents used to treat moderate to severe Alzheimer’s disease. Alzheimer’s disease is a neurological disorder that causes dementia (memory loss), and slowly destroys the ability to think, learn, communicate, and handling daily activities.
Larentine 5 Tablet 10’s contains ‘Memantine’ which is an NMDA receptor antagonist. It acts on the N-methyl-D-aspartate (NMDA) receptors involved in transmitting nerve signals that play an essential role in memory.
Larentine 5 Tablet 10’s decreases the brain’s abnormal activity and may improve the ability to think and remember or might slow the loss of these abilities in people with Alzheimer’s disease.
You can take Larentine 5 Tablet 10’s with or without food. Take Larentine 5 Tablet 10’s as prescribed. You are advised to take Larentine 5 Tablet 10’s for as long as your doctor has prescribed it for you depending on your medical condition.
In some cases, you may experience certain common side-effects such as headache, sleepiness, dizziness, diarrhea, constipation, balance disorders, and high blood pressure. You are advised to talk to your doctor if you experience any of these side-effects persistently.
Please do not stop taking Larentine 5 Tablet 10’s without consulting your doctor. Consult your doctor before taking Larentine 5 Tablet 10’s if you are pregnant or breastfeeding. Avoid driving or operating machinery as Larentine 5 Tablet 10’s causes dizziness, sleepiness, and may affect reactivity. Avoid consuming alcohol along with Larentine 5 Tablet 10’s as it could lead to increased dizziness.
Larentine 5 Tablet 10’s is not recommended for children below 18years as the safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side-effects.
USES OF LARENTINE 5MG
- Treat patients with moderate to severe Alzheimers disease
HOW LARENTINE 5MG WORKS
Glutamate is a chemical that helps to send messages between nerve cells in the brain. In Alzheimers disease nerve cells are damaged resulting in the production of too much of glutamate. This causes more damage to the nerve cells. Memantine protects nerve cells by blocking the effects of excess glutamate without disturbing the normal transmission of nerve signals. Read more: larentine
DIRECTIONS FOR USE
Always take LARENTINE 5MG exactly as your doctor has told you. This medicine must be taken with or without food. Try to take at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine. The recommended dose is one tablet once a day.
SIDE EFFECTS OF LARENTINE 5MG
COMMON
- Headache
- Sleepiness
- Constipation
- Elevated liver function tests
- Dizziness
- Balance disorders
- Shortness of breath
- High blood pressure
- Hypersensitivity
HOW TO MANAGE SIDE EFFECTS
Headache:
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
Sleepiness:
Get up and move around to feel awake. Take a nap to take the edge off the sleepiness. Give your eyes a break to avoid weakness.
Constipation:
Take fibre rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.
Dizziness:
Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.
WARNING & PRECAUTIONS
PREGNANCY
LARENTINE 5MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
LARENTINE 5MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Your doctor will tell you whether your illness allows you to drive and to use machines safely. Also LARENTINE 5MG may change your reactivity, making driving or operating machinery inappropriate.
ALCOHOL
Consumption of alcohol is not recommended during treatment with LARENTINE 5MG.
KIDNEY
LARENTINE 5MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.
LIVER
LARENTINE 5MG should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.
ALLERGY
Do not take LARENTINE 5MG if you are allergic (hypersensitive) to memantine or any other ingredients in this medicine.
HEART DISEASE
LARENTINE 5MG should be used with caution in patients suffering from active heart diseases. Consult your doctor for advice.
OTHERS
Tell your doctor if you have or had conditions such as,
- Have a history of epileptic seizures
- Suffering from high blood pressure
- Severe infections of the urinary tract
INTERACTIONS
Talk to your doctor if you are taking,
- Amantadine (used to treat Parkinsons disease)
- Ketamine (used as an anaesthetic)
- Dextromethorphan (used to treat cough)
- Dantrolene, baclofen
- Cimetidine, ranitidine, procainamide, quinidine, quinine, nicotine
- Hydrochlorothiazide
- Anticholinergics (used to treat movement disorder or intestinal cramps)
- Anticonvulsants (used to prevent and relieve seizures)
- Barbiturates (used to induce sleep)
- Dopaminergic agonists such as L-dopa, bromocriptine
- Neuroleptics (used to treat mental disorders)
- Oral anticoagulants
In-Depth Precautions and Warning
Drug Warnings
Do not take Larentine 5 Tablet 10’s if you are allergic to any of its contents. Inform your doctor if you have/had epilepsy (fits), heart attack, congestive heart failure, or uncontrolled high blood pressure. Talk to your doctor if you change your diet from normal to strict vegetarian or if you are having any kidney problems or urinary tract infections.
Avoid taking amantadine (used to treat Parkinson’s disease), ketamine (anesthetic), dextromethorphan (used to treat cough), and other NMDA-antagonists at the same time. Consult your doctor before taking Larentine 5 Tablet 10’s if you are pregnant or breastfeeding. Avoid driving or operating machinery as Larentine 5 Tablet 10’s causes dizziness, sleepiness, and may affect reactivity.
Avoid consuming alcohol along with Larentine 5 Tablet 10’s as it could lead to increased dizziness. Larentine 5 Tablet 10’s is not recommended for children below 18years as the safety and effectiveness have not been established.
Drug Interactions
Drug-Drug Interactions: Larentine 5 Tablet 10’s may have interaction with antiparkinson’s (amantadine), anaesthetic (ketamine), anti-tussive (dextromethorphan), skeletal muscle relaxant (dantrolene, baclofen), antacid (cimetidine, ranitidine), anti-arrhythmic (procainamide, quinidine), anti-malarial (quinine), an alkaloid (nicotine), diuretic (hydrochlorothiazide), dopaminergic agonist (levodopa, bromocriptine), anti-psychotic (quetiapine), anticonvulsants (used to treat fits), barbiturates (used to induce sleep), neuroleptics (used to treat mental disorders), and oral anticoagulants.
Drug-Food Interactions: Avoid alcohol consumption while taking Larentine 5 Tablet 10’s as it might cause increased dizziness and sleepiness. Avoid smoking as nicotine might interact with working of Larentine 5 Tablet 10’s.
Drug-Disease Interactions: Larentine 5 Tablet 10’s may interact with disease conditions such as high blood pressure, liver or kidney impairment.
SYNOPSIS
Drug | : | Memantine hydrochloride |
Pharmacological Category | : | NMDA receptor antagonists |
Therapeutic Indication | : | Alzheimers disease |
Dosage Forms | : | Tablet, Capsule |
MORE INFORMATION
Store below 20-25°C and keep out of reach of children.
FAQs ABOUT LARENTINE 5MG
Can I just stop taking LARENTINE 5MG?
No, you should not be stopped even if you feel well. This medicine only helps to control the symptoms of Alzheimers disease but does not cure it. If you need to stop this medicine, consult your doctor.
Does LARENTINE 5MG have abuse potential?
No, it does not have abuse potential.
Can LARENTINE 5MG cause headache?
Yes, this medicine may cause headache in some individuals. Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
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