Darbecon 40Mcg/0.4Ml Inj belongs to the class of medication called ‘blood-forming agent‘ primarily used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells’ cancer).
Darbecon 40Mcg/0.4Ml Inj helps to reverse anaemia and reduce the need for blood transfusion. Anaemia occurs when the body has a lower amount of red blood cells or haemoglobin. In chronic kidney disease, the kidney gets damaged and doesn’t filter the blood, leading to anaemia.
Darbecon 40Mcg/0.4Ml Inj contains a protein ‘Darbepoetin alfa‘ which works by providing signals to the bone marrow to make more red blood cells.
Inj is a biologic response modifier and erythropoiesis-stimulating protein. In chronic kidney disease, when the kidney fails to produce sufficient ‘erythropoietin protein’ which aids in the formation of red blood cells, Inj stimulates the production of this protein in the bone marrow.
Darbecon 40Mcg/0.4Ml Inj comes in the formulation of injection that should be injected by the healthcare provider. Do not self-administer.
The most common side effects of Inj are shortness of breath, cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain.
Most of these sides effects of Darbecon 40Mcg/0.4Ml Inj do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
If you have uncontrolled/untreated high blood pressure or red cell aplasia (a type of anaemia) due to darbepoetin alfa or epoetin alfa, please inform your doctor before taking Inj to avoid any complications.
Also, mention all the other medications you are taking to affect the way Inj works. Inform your doctor immediately, if you feel weak, lightheaded, tired, or short of breath, or if your skin looks pale as it may be signs that the body has stopped responding to Inj. Read more:
Uses of Darbecon 40Mcg/0.4Ml Inj
Anaemia (in cancer and chronic kidney disease)
Medicinal Benefits
Darbecon 40Mcg/0.4Ml Inj is a human-made form of naturally occurring erythropoiesis-stimulating protein or erythropoietin (a hormone produced by the kidney’s specialized cells and is responsible for protecting red blood cells against destruction and also stimulates the cells of bone marrow to produce more amount of red blood cells).
Deficiency of erythropoietin happens when a person is suffering from chronic kidney diseases, which in turn cause low red blood cells count causing anaemia.
This medicine is primarily indicated for treating anaemia (low red blood cell count) in persons with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer except for bone marrow or blood cells’ cancer.
Inj contains a protein ‘Darbepoetin alfa’ which works by providing signals to the bone marrow to make more red blood cells.
Darbecon 40 Injection is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone marrow to produce more red blood cells.
Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional.
It may cause side effects like high blood pressure and hypersensitivity. Inform your doctor if there are symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures).
Your doctor may get your blood tests done regularly to monitor the levels of salts (electrolytes such as potassium), hemoglobin, and blood cells in your blood. You should stop taking it and consult with a doctor if you develop shortness of breath or skin rash. click here
Directions for Use
Storage
Side Effects of Darbecon 40Mcg/0.4Ml Inj
- Shortness of breath
- Cough
- Hypotension (low blood pressure)
- Headache
- Body aches
- Diarrhoea
- Injection site pain
- Abdominal pain (stomach pain)
BENEFITS OF DARBECON INJECTION
In Treatment of Anemia due to chronic kidney disease
In Treatment of Anemia due to cancer chemotherapy
In-Depth Precautions and Warning
Drug Warnings
Darbecon 40Mcg/0.4Ml Inj can enhance the risk of serious heart problems including heart attack so tell your doctor immediately if you notice shortness of breath, sudden numbness or weakness, chest pain, or trouble speaking or understanding.
This medicine may also shorten survival time in some people with certain types of cancer. Inform your doctor before taking Inj if you have heart disease, high blood pressure, kidney disease, stroke, heart attack, blood clot, seizure, or latex allergy.
Do not take Inj if you are pregnant or breastfeeding unless prescribed by the doctor. Darbecon 40Mcg/0.4Ml Inj may affect a person’s ability to drive as it may cause convulsion during initial days of treatment, so a person taking Inj should avoid driving or operating any machine.
Darbecon 40Mcg/0.4Ml Inj should not be given to children below 12 years of age, as safety and effectiveness have not been established. Avoid consuming alcohol along with Inj as it could lead to increased dizziness and sleepiness.
Drug Interactions
Drug-Drug Interactions: Darbecon 40Mcg/0.4Ml Inj may have interaction with other chemotherapy drugs (thalidomide), immunosuppressant medication (cyclosporine), antihypertensive medicines (captopril).
Drug-Food Interactions: Avoid alcohol consumption while taking Inj as it might cause increased dizziness and sleepiness.
Drug-Disease Interactions: Darbecon 40Mcg/0.4Ml Inj may have interactions with disease conditions such as seizures, hemodialysis, hypertension, and thrombotic events
Safety Advice
-
ALCOHOL
CONSULT YOUR DOCTOR
Avoid consumption of alcohol while taking Inj as it may increase dizziness and sleepiness.
-
PREGNANCY
Avoid taking Inj if you are pregnant unless prescribed by a doctor as Darbecon 40Mcg/0.4Ml Inj is a pregnancy category C drug. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.
-
BREAST FEEDING
Consult your doctor before taking Darbecon 40Mcg/0.4Ml Inj; your doctor will decide whether Darbecon 40Mcg/0.4Ml Inj can be taken by breastfeeding mothers or not.
-
DRIVING
CONSULT YOUR DOCTOR
Darbecon 40Mcg/0.4Ml Inj causes convulsions (seizures), especially during the initial months of treatment. So, it is better not to drive or operate machinery unless you are alert.
-
LIVER
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
-
KIDNEY
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Habit Forming
Diet & Lifestyle Advise
- Limit the consumption of fluids, salt, potassium, phosphorous, and other electrolytes.
- Eat a low-protein diet, and get enough calories from the foods if you are losing weight.
- Eat foods that are high in vitamin B12, iron, and folic acid can fulfil the deficiencies of happed in kidney disease.
- Include a little number of healthy fats in your diet that give you enough energy to be active during the day; however, try to limit fats that make you fatty. Try to include olive oil, peanut oil, and corn oil into your diet.
- Rest well, get plenty of sleep.
- Avoid smoking and alcohol consumption.
- Using essential oils for massages can help increase circulation.
Special Advise
- Certain diagnostic tests like Complete blood count (CBC) can help check the count of red blood cells.
- Have regular haemoglobin tests to check whether there is an improvement in the level of red blood cells after taking Darbecon 40Mcg/0.4Ml Inj or not.
Disease/Condition Glossary
Anaemia: It occurs when the body has a lower amount of red blood cells or haemoglobin than normal haemoglobin (iron-rich the protein responsible for allowing red blood cells to carry more oxygen from the lungs to the rest of the body).
In chronic kidney disease, the kidney gets damaged and doesn’t filter the blood, leading to anaemia. Symptoms of anaemia in chronic kidney disease include fatigue or tiredness, shortness of breath, ashen skin, weakness, body aches, chest pain, dizziness, fainting, fast or irregular heartbeat, headache, sleep problems, and trouble in concentrating.
FAQs
Q. How long does it take for Darbecon 40 Injection to start working?
Q. Is Darbecon 40 Injection safe to use?
Q. Other than PRCA, can there be other reasons for not responding to Darbecon 40 Injection?
Q. Can Darbecon 40 Injection be used in children?
Q. Can Darbecon 40 Injection affect blood pressure?
Be the first to review “DARBECON 40 Injection”
Related products
Anaemia
Anaemia
Anaemia
Anaemia
Anaemia
Anaemia
Anaemia
Anaemia
Reviews
There are no reviews yet.