Tacmod Forte 0.1% Ointment

TACMOD FORTE 0.1% contains Tacrolimus which belongs to the group of medicines called immunosuppressants. It is used to treat moderate to severe atopic dermatitis (eczema) in adult patients, who are not adequately responsive for conventional therapies like topical corticosteroids.

It can also be used as a maintenance therapy, for the prevention of flares and prolongation of flare-free intervals in patients having a high frequency of disease exacerbations (4 or more times/year) who had an initial response up to 6 weeks of treatment.

Atopic dermatitis is an auto-immune skin disease, in which your skin becomes inflamed, red and itchy. Tacrolimus alters this abnormal immune function and relieves your skin from inflammation and itching.

The most common side effects of applying this medicine are itching and burning sensation on the skin. This side effects are mild-moderate and generally disappears within 1 week of therapy.

Avoid consumption of alcohol while using this medicine, because drinking alcohol might cause your face or skin to become flushed. Limit your exposure to sun and UV light, because immunosuppressants could increase the risk of skin cancer.

Always wear loose fitting clothes and sunscreen that protects your skin from sun. This medicine is not recommended for use in children younger than 16 years of age. Consult your doctor before using.

Tacmod Forte Ointment is used to treat eczema (atopic dermatitis). It works by suppressing the activity of certain immune cells that cause inflammation (redness and swelling) of the skin. This relieves itching and improves rashes in atopic dermatitis.

Tacmod Forte Ointment is used for external use. It should be used 2-4 times a day on the affected area or use it as suggested by the doctor.

It should be applied slowly and evenly to the skin until it is rubbed in. You should not use it too often and you should not cover the treated area with a bandage or plaster. You must inform your doctor if there’s no improvement even after two weeks of treatment or if the skin gets worse.

It is a safe medicine with few side effects, but you may get an application site reaction like burning, irritation, itching, and redness. This medicine is not normally recommended during pregnancy or while breastfeeding unless it is clearly needed.

USES OF TACMOD FORTE 0.1%:

Treats and prevents moderate to severe atopic dermatitis (eczema) in adults

HOW TACMOD FORTE 0.1% WORKS:

Tacrolimus binds to an intracellular protein called FK binding protein-12. The tacrolimus-FK binding protein-12 complex inhibits the activity of calcineurin (a calcium-dependent phosphatase transmitting chemical), which in turn, reduces the activity of T-lymphocytes in the immune system. As a result, the T-cells fail to release their cytokines that cause inflammation, redness and itching.

DIRECTIONS FOR USE:

Apply this medicine as directed by your physician. It is for external use only. Apply a thin layer of the medicine to affected areas of your skin. It can be used on your face, neck, elbows and knees. Do not cover the treated skin with bandages. Wash your hands after application.

Avoid contact of this medicine with eyes, ears, nose or mouth, if happens wipe it or rinse it thoroughly with water. Continue to use this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF TACMOD FORTE 0.1% OINTMENT 30GM:

COMMON

Itching and burning sensation on the skin
Skin tingling, rash, redness or pain
Increased skin sensitivity
Local skin infection (infected hair follicles, generalized herpes simplex infections)

HOW TO MANAGE SIDE EFFECTS:

Skin tingling
Rash
Redness
Pain

Avoid hot water showers since it can irritate the skin. Pat dry your skin after bath. Do not rub/scratch the infected area and avoid using perfumed soaps or deodorants. Excessive sun exposure should be avoided.

INTERACTIONS:

Talk to your doctor, if you are using any other topical medicines.

SYNOPSIS:

Drug : Tacrolimus
Pharmacological Category : Immunosuppressants, Calcineurin Inhibitor
Therapeutic Indication : Atopic dermatitis
Dosage Forms : Tablet, Capsule ,Cream, Ointment, Lotion, Eye ointment, Topical solution

MORE INFORMATION:

Store below 20-25°C and keep out of reach of children.

FAQ’s ABOUT TACMOD FORTE 0.1%:

Q: Can TACMOD FORTE 0.1% be used in children?
A: This medicine is not recommended for use in children younger than 16 years of age. Consult your doctor before using.

Q: Can TACMOD FORTE 0.1% used to treat acne?
A: This medicine is used to treat and prevent atopic dermatitis.

Q: Can TACMOD FORTE 0.1% cause cancer?
A: Yes. Limit your exposure to sun and UV light, because immunosuppressants could increase the risk of skin cancer. Wear appropriate protective clothing and use a sunscreen with a high sun protection factor.

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to Ointment or any other medicines, please tell your doctor. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Tacmod Forte Ointment 30 gm. Avoid alcohol consumption with Tacmod Forte Ointment 30 gm as it may increase the risk of severe adverse effects.

Drive only if you are alert as Tacmod Forte Ointment 30 gm may cause drowsiness, dizziness or vision problems. Do not cover or wrap the treated area with bandage or dressing.  Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) in contact with Tacmod Forte Ointment 30 gm catches fire and burns easily.

Please avoid contact with eyes, nose or mouth as it may irritate. Do not shower, bathe or swim immediately after applying Tacmod Forte Ointment 30 gm as it may wash off Tacmod Forte Ointment 30 gm.

In case Tacmod Forte Ointment 30 gm comes in contact with these areas accidentally, rinse with water thoroughly. Do not swallow Tacmod Forte Ointment 30 gm. In case of accidental swallowing, consult a doctor immediately.

Drug Interactions

Drug-Drug Interaction: Ointment may interact with immunosuppressant (ciclosporin), antibiotics (fluconazole, itraconazole, ketoconazole, clotrimazole, voriconazole, erythromycin, clarithromycin, rifampicin), antiemetic (metoclopramide), anticonvulsants (phenytoin, phenobarbital), antacids (lansoprazole, cimetidine, omeprazole),

steroid (cortisone, prednisolone, methylprednisolone), antivirals (aciclovir), pain reliever (ibuprofen), an antidepressant (nefazodone), anticancer drugs (imatinib, nilotinib), anti-HIV drugs (nelfinavir, saquinavir, ritonavir).

Drug-Food Interaction: Ointment may interact with St. John’s Wort (a herbal supplement to treat depression) or extracts of Schisandra sphenanthera. Avoid taking grapefruit and grapefruit juice with Tacmod Forte Ointment 30 gm as it may cause serious side effects.

Also, avoid consumption of alcohol with Tacmod Forte Ointment 30 gm as it may cause flushing (make face or skin feel warm and hot) and increase other adverse effects.

Drug-Disease Interaction: If you have skin tumours, weakened immune system, infected lesions, cutaneous Graft Versus Host Disease (an immune reaction of the skin in patients who had bone marrow transplant), generalised erythroderma (inflammatory scaling and redness of entire skin), Netherton’s syndrome, lamellar ichthyosis

(extensive scaling of skin), diarrhoea for more than a day, stomach pain with or without symptoms such as nausea, chills, fever or vomiting, liver or heart problems, inform your doctor before taking Tacmod Forte Ointment 30 gm.

Safety Advice

• 

  ALCOHOL

  CONSULT YOUR DOCTOR

  Avoid alcohol consumption with Ointment 30 gm as it may increase the risk of severe adverse effects. Please consult a doctor before consuming alcohol with Ointment 30 gm.

• 

  PREGNANCY

  Ointment 30 gm is Category C pregnancy drug and is given to a pregnant woman only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant before using Tacmod Forte Ointment 30 gm.

• 

  BREAST FEEDING

  CONSULT YOUR DOCTOR

  Tacmod Forte Ointment 30 gm may be excreted in human milk and is not recommended for breastfeeding mothers as it may cause adverse effects in the baby. However, please consult a doctor if you are breastfeeding before taking Tacmod Forte Ointment 30 gm.

• 

  DRIVING

  Tacmod Forte Ointment 30 gm may cause drowsiness, dizziness or vision problems. Therefore, avoid driving if experience any of these symptoms after taking Tacmod Forte Ointment 30 gm.

• 

  LIVER

  Please consult a doctor if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

• 

  KIDNEY

  Please consult a doctor if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.