BEVACIREL 400MG contains Bevacizumab which belongs to a group of medicines called antiangiogenic agents.
It is indicated to treat metastatic colorectal cancer, first-line non-squamous non small cell lung cancer, recurrent glioblastoma (GBM), metastatic renal cell carcinoma, persistent, recurrent, or metastatic cervical cancer, epithelial ovarian, fallopian tube, or primary peritoneal cancer and hepatocellular carcinoma.
Bevacizumab is a humanized monoclonal IgG1 antibody which contains human framework regions and murine complementarity determining regions.
This binds VEGF and prevents the interaction of VEGF to its receptors (Flt-1 and KDR) on the surface of endothelial cells.
This interaction of VEGF with its receptors leads to endothelial cell proliferation and new blood vessel formation in invitro models of angiogenesis. Bevacizumab reduces microvascular growth and inhibition of metastatic disease progression.
Before receiving this BEVACIREL 400MG, tell your physician if you have liver, kidney or heart problems, are pregnant or breastfeeding.
This medicine is not suitable for use in children and adolescents below 18 years of age.
The common side effects are nose or rectal bleeding, headache, back pain or increased blood pressure.
USES OF BEVACIREL 400MG
Treats,
- Metastatic colorectal cancer
- First-line non-squamous non small cell lung cancer
- Recurrent glioblastoma (GBM)
- Metastatic renal cell carcinoma
- Persistent, recurrent, or metastatic cervical cancer
- Epithelial ovarian
- Fallopian tube, or primary peritoneal cancer and
- Hepatocellular carcinoma
HOW BEVACIREL 400MG WORKS
Bevacizumab belongs to antiangiogenic agents which works by stopping the formation of blood vessels that bring oxygen and nutrients to tumors and slows the growth and spread of tumors.
DIRECTIONS FOR USE
BEVACIREL 400MG will be administered as an intravenous infusion by your doctor or nurse.
SIDE EFFECTS OF BEVACIREL 400MG
COMMON
- Nosebleed or rectal bleeding
- Increased blood pressure
- Headache
- Back pain
- Dry or watery eyes
- Flaky or dry skin
- Runny nose or sneezing
- Changes in your sense of taste
HOW TO MANAGE SIDE EFFECTS
Headache:
Rest and drink plenty of fluids. Apply a wet or cold cloth to forehead and rest in a quiet, comfortable, dark room.
Back pain:
Use an ice pack or over the counter medicines to relieve pain.
INTERACTIONS
Tell your doctor if you are taking,
- Paclitaxel
- Carboplatin
SYNOPSIS
Drug | : | Bevacizumab |
Pharmacological Category | : | Antiangiogenic agents |
Therapeutic Indication | : | Metastatic colorectal cancer, First-line non-squamous non small cell lung cancer, Hepatocellular carcinoma |
Dosage Forms | : | Injection |
MORE INFORMATION
- Keep out of reach of children
- Store at 2 8°C
FAQs ABOUT BEVACIREL 400MG
Can BEVACIREL 400MG be used during pregnancy?
It is not suitable for use in pregnant women, unless prescribed by your doctor.
How BEVACIREL 400MG works differently from chemotherapy?
It prevents the growth of new blood vessels that feed tumors and causes the tumour to shrink, or to stop growing.
How is BEVACIREL 400MG given?
It will be administered intravenously by your doctor or nurse.
PRODUCT INTRODUCTION
It is used in the treatment of cancer of colon and rectum, non-small cell lung cancer, kidney cancer, brain tumor, ovarian and cervical cancer.
It helps to prevent the growth of new blood vessels that feed tumors and stops tumors from growing.
Bevacirel 400 mg Injection is an effective medicine, first-line option when used together with other cancer medicines.
That means you get it through a small needle in your vein or through a port, which is a device placed under your skin.
The doctor will decide your dose and duration and will check you for signs of an infusion reaction such as high blood pressure and trouble breathing.
You keep taking Bevacirel 400mg Injection as long as your disease is controlled and your side effects are manageable.
Your doctor will determine whether you should stop taking it or not.
You may be advised to check blood pressure and levels of protein in urine while you are taking this medication. click here : Bevacirel 400
most common side effects
Inform your doctor that you are taking this medication before undergoing any surgical procedure, as the drug has ability to lower the ability of wound healing.
Other than this, it also enhances your risk of bleeding thus if you notice any unusual bleeding or bleeding consult with your doctor immediately.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.
USES OF BEVACIREL INJECTION
- Cancer of colon and rectum
- Non-small cell lung cancer
- Kidney cancer
- Brain tumor
- Ovarian cancer
- Cervical cancer
BENEFITS OF BEVACIREL INJECTION
In Cancer of colon and rectum
It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor.
In Non-small cell lung cancer
Bevacirel 400mg Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines.
It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor.
In Kidney cancer
It stops cancer growth and prevents multiplication of cancer cells.
This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.
In Brain tumor
Bevacirel 400mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Consult your doctor if you have any doubts.
In Ovarian cancer
It usually spreads to the pelvis and stomach. Bevacirel 400mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells.
It is an effective medicine but has some side effects that may be bothersome.
So, you should discuss the risks and benefits with your doctor.
In Cervical cancer
The affected female may have symptoms such as abnormal bleeding, foul smelling vaginal discharge, lower back pain, or may even have no symptoms at all.
It has a lot of side effects and you must discuss the risks and benefits with your doctor before starting treatment with this medicine.
SIDE EFFECTS OF BEVACIREL INJECTION
Common side effects of Bevacirel
- Rectal bleeding
- Taste change
- Headache
- Nosebleeds
- Back pain
- Dry skin
- High blood pressure
- Protein in urine
- Inflammation of the nose
HOW TO USE BEVACIREL INJECTION
HOW BEVACIREL INJECTION WORKS
SAFETY ADVICE
Alcohol
Pregnancy
Breast feeding
Driving
Sleepiness and fainting have been reported with Bevacirel 400mg Injection and this may impair your ability to drive.
Kidney
Liver
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