Cizumab 400 Solution for Infusion is an effective medicine, first-line option when used together with other cancer medicines. It is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. The doctor will decide your dose and duration and will check you for signs of an infusion reaction such as high blood pressure and trouble breathing. You keep taking Cizumab 400 Solution for Infusion as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking it or not. You may be advised to check blood pressure and levels of protein in urine while you are taking this medication.
The most common side effects of this medicine include rectal bleeding, taste change, and headache. Inform your doctor that you are taking this medication before undergoing any surgical procedure, as the drug has ability to lower the ability of wound healing. Other than this, it also enhances your risk of bleeding thus if you notice any unusual bleeding or bleeding consult with your doctor immediately.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.
CIZUMAB 400 contains Bevacizumab which belongs to a group of medicines called antiangiogenic agents. It is indicated to treat metastatic colorectal cancer, first-line non-squamous non small cell lung cancer, recurrent glioblastoma (GBM), metastatic renal cell carcinoma, persistent, recurrent, or metastatic cervical cancer, epithelial ovarian, fallopian tube, or primary peritoneal cancer and hepatocellular carcinoma.
Bevacizumab is a humanized monoclonal IgG1 antibody which contains human framework regions and murine complementarity determining regions. This binds VEGF and prevents the interaction of VEGF to its receptors (Flt-1 and KDR) on the surface of endothelial cells. This interaction of VEGF with its receptors leads to endothelial cell proliferation and new blood vessel formation in invitro models of angiogenesis. Bevacizumab reduces microvascular growth and inhibition of metastatic disease progression.
Before receiving this CIZUMAB 400, tell your physician if you have liver, kidney or heart problems, are pregnant or breastfeeding. This medicine is not suitable for use in children and adolescents below 18 years of age. The common side effects are nose or rectal bleeding, headache, back pain or increased blood pressure.
USES OF CIZUMAB 400
Treats,
- Metastatic colorectal cancer
- First-line non-squamous non small cell lung cancer
- Recurrent glioblastoma (GBM)
- Metastatic renal cell carcinoma
- Persistent, recurrent, or metastatic cervical cancer
- Epithelial ovarian
- Fallopian tube, or primary peritoneal cancer and
- Hepatocellular carcinoma
HOW CIZUMAB 400 WORKS
Bevacizumab belongs to antiangiogenic agents which works by stopping the formation of blood vessels that bring oxygen and nutrients to tumors and slows the growth and spread of tumors.
DIRECTIONS FOR USE
CIZUMAB 400 will be administered as an intravenous infusion by your doctor or nurse.
SIDE EFFECTS OF CIZUMAB 400
COMMON
- Nosebleed or rectal bleeding
- Increased blood pressure
- Headache
- Back pain
- Dry or watery eyes
- Flaky or dry skin
- Runny nose or sneezing
- Changes in your sense of taste
HOW TO MANAGE SIDE EFFECTS
Headache:
Rest and drink plenty of fluids. Apply a wet or cold cloth to forehead and rest in a quiet, comfortable, dark room.
Back pain:
Use an ice pack or over the counter medicines to relieve pain.
INTERACTIONS
Tell your doctor if you are taking,
- Paclitaxel
- Carboplatin
SYNOPSIS
| Drug | : | Bevacizumab |
| Pharmacological Category | : | Antiangiogenic agents |
| Therapeutic Indication | : | Metastatic colorectal cancer, First-line non-squamous non small cell lung cancer, Hepatocellular carcinoma |
| Dosage Forms | : | Injection |
MORE INFORMATION
- Keep out of reach of children
- Store at 2 8°C
FAQs ABOUT CIZUMAB 400
Can CIZUMAB 400 be used during pregnancy?
It is not suitable for use in pregnant women, unless prescribed by your doctor.
How CIZUMAB 400 works differently from chemotherapy?
It prevents the growth of new blood vessels that feed tumors and causes the tumour to shrink, or to stop growing.
How is CIZUMAB 400 given?
It will be administered intravenously by your doctor or nurse.
PRODUCT INTRODUCTION
It is used in the treatment of cancer of colon and rectum, non-small cell lung cancer, kidney cancer, brain tumor, ovarian and cervical cancer.
It helps to prevent the growth of new blood vessels that feed tumors and stops tumors from growing.
Cizumab 400 Solution for Infusion is an effective medicine, first-line option when used together with other cancer medicines. It is given as an infusion.
That means you get it through a small needle in your vein or through a port, which is a device placed under your skin.
The doctor will decide your dose and duration and will check you for signs of an infusion reaction such as high blood pressure and trouble breathing.
You keep taking Cizumab 400 Solution for Infusion as long as your disease is controlled and your side effects are manageable.
Your doctor will determine whether you should stop taking it or not. You may be advised to check blood pressure and levels of protein in urine while you are taking this medication. click here : Cizumab 400
most common side effects
Inform your doctor that you are taking this medication before undergoing any surgical procedure, as the drug has ability to lower the ability of wound healing.
Other than this, it also enhances your risk of bleeding thus if you notice any unusual bleeding or bleeding consult with your doctor immediately.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.
USES OF CIZUMAB SOLUTION FOR INFUSION
- Cancer of colon and rectum
- Non-small cell lung cancer
- Kidney cancer
- Brain tumor
- Ovarian cancer
- Cervical cancer
BENEFITS OF CIZUMAB SOLUTION FOR INFUSION
In Cancer of colon and rectum
In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue.
Cizumab 400 Solution for Infusion treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer.
It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells.
It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor.
In Non-small cell lung cancer
Cizumab 400 Solution for Infusion helps treat non-small cell lung cancer and may be given alone or in combination with other medicines.
It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.
In Kidney cancer
It stops cancer growth and prevents multiplication of cancer cells.
This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.
In Brain tumor
Cizumab 400 Solution for Infusion kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Consult your doctor if you have any doubts.
In Ovarian cancer
It usually spreads to the pelvis and stomach. Cizumab 400 Solution for Infusion kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells.
It is an effective medicine but has some side effects that may be bothersome. So, you should discuss the risks and benefits with your doctor.
In Cervical cancer
The affected female may have symptoms such as abnormal bleeding, foul smelling vaginal discharge, lower back pain, or may even have no symptoms at all.
SIDE EFFECTS OF CIZUMAB SOLUTION FOR INFUSION
Consult your doctor if they persist or if you’re worried about them
Common side effects of Cizumab
- Rectal bleeding
- Taste change
- Headache
- Nosebleeds
- Back pain
- Dry skin
- High blood pressure
- Protein in urine
- Inflammation of the nose
HOW TO USE CIZUMAB SOLUTION FOR INFUSION
HOW CIZUMAB SOLUTION FOR INFUSION WORKS
This stops the formation of blood vessels that bring oxygen and nutrients to cancerous cells.
SAFETY ADVICE
Alcohol
Pregnancy
Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
Driving
Sleepiness and fainting have been reported with Cizumab 400 Solution for Infusion and this may impair your ability to drive.
Kidney
Liver
WHAT IF YOU FORGET TO TAKE CIZUMAB SOLUTION FOR INFUSION?
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