Lenangio 10 mg Capsule

WHAT IS LENANGIO 10MG?

LENANGIO 10MG contains Lenalidomide which belongs to a group of medicines which affect how your immune system works

WHAT LENANGIO 10MG IS USED FOR?

LENANGIO 10MG is used to treat in adults for:

Multiple myeloma
Myelodysplastic syndromes (MDS)
Mantle cell lymphoma (MCL)

WARNING AND PRECAUTIONS:

TALK TO DOCTOR

Talk to your doctor before taking this medicine, if you:

Are allergic (hypersensitive) to LENANGIO 10MG or any of the other ingredients of this medicine
Have had blood clots in the past
Have any signs of an infection, such as a cough or fever
Have or ever had previous viral infection, particularly hepatitis B infection, varicella zona, HIV
Have kidney problems
Have had a heart attack
Have MDS, you may be more likely to get a condition called acute myeloid leukemia (AML)

PREGNANCY & BREAST FEEDING

LENANGIO 10MG should not be taken in pregnant, as it is expected to be harmful to an unborn baby
You must not become pregnant while taking LENANGIO 10MG. Therefore, you must use effective methods of contraception if you are a woman of childbearing potential
You must not breast-feed when taking LENANGIO 10MG, as it is not known if LENANGIO 10MG passes into human milk

CHILDREN & ADOLESCENTS

LENANGIO 10MG is not recommended for use in children and adolescents under 18 years

DRIVING & USING MACHINES

Do not drive or operate machines if you feel dizzy, tired, sleepy, have vertigo or blurred vision after taking LENANGIO 10MG

INTERACTIONS:

Tell your doctor if you are taking,

Medicines used to prevent pregnancy such as oral contraceptives, as they may stop working
Digoxin used for heart problems
Warfarin used to thin the blood

DIRECTIONS & FOR USE:

Always take this medicine exactly as your doctor has told you
Swallow the medicine whole, preferably with water
This medicine can be taken either with or without food
If you take more LENANGIO 10MG

If you have taken more LENANGIO 10MG than you should, talk to your doctor or local hospital accident and emergency department
If you forget to take LENANGIO 10MG

If you forget to take LENANGIO 10MG at your regular time and less than 12 hours have passed – take your dose immediately. more than 12 hours have passed – do not take the medicine. Take your next dose at the usual time the next day
If you Stop to take LENANGIO 10MG

Do not stop taking LENANGIO 10MG until the doctor has told you to do so

SIDE EFFECTS OF LENANGIO 10MG:

SERIOUS

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Reduce the number of white blood cells, blood cells which help the blood to clot (platelets) which may lead to bleeding disorders such as nosebleeds and bruising
Blood clots in the veins (thrombosis).
Fever, chills, sore throat, cough, mouth ulcers or any other symptoms of infection including within the bloodstream (sepsis)
Bleeding or bruising in the absence of injury
Chest pain or leg pain
Shortness of breath

COMMON

Like all medicines, this medicine can cause side effects, although not everybody gets them.

A fall in the number of red blood cells which may cause anemia leading to tiredness and weakness constipation, diarrhoea, nausea, redness of skin, rashes, vomiting, muscle cramps, muscle aches, bone pain, joint pain, tiredness, generalized swelling including swelling of your arms and legs
Decreased appetite, low levels of potassium in the blood, leg pain, chest pain or shortness of breath
Infection of the lungs, upper respiratory tract, shortness of breath
Blurred vision, clouding of your eye (cataract)
Kidney problems
Changes to a protein in the blood that can cause swelling of the arteries (vasculitis)
Increases in your blood sugar level (diabetes)
Increase in pain, tumor size, redness around the tumor
Increased blood pressure or a fall in blood pressure, slow, fast or irregular heart beat
Difficulty getting an erection
Stroke, fainting, muscle weakness, joint swelling
Changes to blood thyroid hormone, low levels of calcium, phosphate or magnesium in the blood
Depression, deafness, abnormal liver test results, impaired balance, difficulty moving, ringing in the ears (tinnitus)
An excess of iron in the body
Thirst, confusion, toothache, weight loss

UNCOMMON

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Bleeding within the skull
Circulatory problems
Loss of vision
Loss of sex drive (libido)
Passing large amount of urine with bone pain and weakness, which may be symptoms of a kidney disorder (fanconi syndrome)
Stomach pain, bloating marked by inflammation in the large intestine (called colitis or caecitis)
Renal tubular necrosis

RARE

Like all medicines, this medicine can cause side effects, although not everybody gets them.

High potassium,
Phosphorus,
Uric acid,
Low calcium consequently leading to changes in kidney function,
Heartbeat,
Seizures,
Sometimes death

STORAGE:

Protect from excess heat and light
Keep this medicine out of reach of children
Store at room temperature (15-25°C)
Do not use this medicine after the expiry date

PRODUCT INTRODUCTION

Some common side effects

In Multiple myeloma

If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break.

Lenangio 10 Capsule may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma.

This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body.

Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.

In Lepra reaction

Lepra reactions are complicated inflammatory reactions that may occur before, during or after the treatment for leprosy, a serious bacterial skin disease.
These reactions increase nerve damage and worsen disability in leprosy patients.

Therefore lepra reactions need treatment with medicines such as Lenangio 10 Capsule in order to stimulate the immune system and aid in recovery.

This medicine will also prevent further damage due to lepra reactions. Take it as prescribed by the doctor to get the most benefit.

SIDE EFFECTS OF LENANGIO CAPSULE

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lenangio

• Headache
• Weakness
• Nausea
• Rash
• Dizziness
• Sleepiness
• Edema (swelling)
• Loss of appetite
• Decreased white blood cell count
• Decreased calcium level in blood
• Weight gain
• Muscle weakness
• Fatigue
• Fever
• Anxiety
• Blood clots
• Dry skin
• Weight loss
• Confusion
• Decreased white blood cell count (neutrophils)
• Neuropathy
• Constipation
• Tremors

HOW TO USE LENANGIO CAPSULE

Take this medicine in the dose and duration as advised by your doctor. Lenangio 10 Capsule may be taken with or without food, but it is better to take it at a fixed time.

HOW LENANGIO CAPSULE WORKS

Lenangio 10 Capsule is an anti-cancer medication. It works by enhancing the immune system that indirectly attacks the cancer cells.

It prevents the growth of new blood vessels within the tumor. It also restricts the production of chemical messengers (cytokine and growth factor) which are responsible for the growth of cancer cells. This is how it works against cancer.

SAFETY ADVICE

Alcohol

It is not known whether it is safe to consume alcohol with Lenangio 10 Capsule. Please consult your doctor.

Pregnancy

Lenangio 10 Capsule is highly unsafe to use during pregnancy. Seek your doctor’s advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

Lenangio 10 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

Lenangio 10 Capsule may cause side effects which could affect your ability to drive.
You may feel dizzy, tired, sleepy, have vertigo or blurred vision after taking Lenangio 10 Capsule and this may affect your ability to drive.

Kidney

Lenangio 10 Capsule should be used with caution in patients with kidney disease. Dose adjustment of Lenangio 10 Capsule may be needed. Please consult your doctor.

Liver

Lenangio 10 Capsule should be used with caution in patients with liver disease. Dose adjustment of Lenangio 10 Capsule may be needed. Please consult your doctor.

WHAT IF YOU FORGET TO TAKE LENANGIO CAPSULE?

If you miss a dose of Lenangio 10 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.