Soranib 200 mg Tablet

SORANIB contains Sorafenib which belongs to the group of medicines called antineoplastic agents. It is used to treat liver and thyroid cancer.

It can also be used to treat advanced cancer of kidney, when standard therapy cannot cure the disease. Sorafenib works by slowing down the rate of growth of tumor cells and arrests blood supply to them.

This medicine can be taken either without food or with a low-to-moderate fat meal. Do not take this medicine with high fat meals, because this may make SORANIB less effective.

It is important to take this medicine at same time each day, so that there is a steady concentration in your bloodstream.

During the treatment, your doctor would monitor your blood pressure and blood sugar levels regularly to avoid any unwanted side effects.

The most common side effects of taking this medicine are nausea, vomiting, diarrhea, hair loss, headache, muscle pain and mouth sores.

Before taking this medicine, inform your doctor if you have severe kidney or liver impairment. While taking this medicine, avoid becoming pregnant.

If you could become pregnant use an adequate contraceptive method. Do not breastfeed while taking this medicine, because it may interfere with the growth and development of your baby.

This medicine is generally not recommended for use in children. Consult your doctor before taking.

USES OF SORANIB:

Treats liver cancer (hepatocellular carcinoma)
Treats thyroid cancer (differentiated thyroid carcinoma)
Treats advanced uncontrollable kidney cancer (advanced renal cell carcinoma)

HOW SORANIB WORKS:

Sorafenib is a tyrosine kinase inhibitor that acts by decreasing the proliferation of tumor cells. It inhibits various intracellular and cell surface kinases, that are responsible for tumor growth, tumor cell signaling, angiogenesis and arrests blood supply to the cancer cells which results in apoptosis (death of cells).

DIRECTIONS FOR USE:

Take this medicine as directed by your physician. It can be taken either without food or with a low-to-moderate fat meal. Try to take this medicine at same time each day. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Your doctor will decide the correct dose for you depending upon your condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF SORANIB:

COMMON

Diarrhea, nausea or vomiting
Feeling weak or tired
Mouth pain, tongue pain, abdominal pain
Headache
Joint pain or tumor pain
Hair loss
Painful palms or soles
Dry skin, rash or itching
High blood pressure
Fever or infections
Loss of appetite, indigestion, constipation, weight loss
Difficulty in swallowing
Depression
Sexual impotence
Dysphonia (change in voice)
Chest pain
Tinnitus (ringing in the ear)
Anemia (decrease in red blood cells)
Underactive thyroid gland
Dysgeusia (distortion of sense of taste)
Flushing (redness in face and often other areas of skin)
Runny nose
Heartburn

RARE

Allergic reaction (such as skin rash, painful blisters and fever, swelling of skin, difficulty in breathing or swallowing)
Symptoms of liver damage (nausea, vomiting, abdominal pain and jaundice)

HOW TO MANAGE SIDE EFFECTS:

Nausea or vomiting:

Try taking this medicine with, or just after meal. Stick to simple meals. Do not eat rich or spicy food.

Constipation:

Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.

Diarrhea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

INTERACTIONS:

Talk to your doctor, if you are taking,

Rifampicin, neomycin or other medicines used to treat infections
St John?s wort (a herbal treatment used to treat depression)
Medicines used to treat epilepsy (e.g. phenytoin, carbamazepine or phenobarbital)
Dexamethasone (a corticosteroid used for various conditions)
Anticoagulants used to prevent blood clots (e.g. warfarin or phenprocoumon)
Other medicines used to treat cancer (doxorubicin, capecitabine, docetaxel, paclitaxel and irinotecan)
Digoxin (used to treat mild to moderate heart failure)

SYNOPSIS:

Drug : Sorafenib
Pharmacological Category : Antineoplastic Agents, Tyrosine Kinase Inhibitors
Therapeutic Indication : Liver cancer, Thyroid cancer, Advanced kidney cancer
Dosage Forms : Tablet

MORE INFORMATION:

Store below 20-25°C and keep out of reach of children.

FAQ’s ABOUT SORANIB:

Q: Can SORANIB cure hepatocellular carcinoma?
A: Yes. This medicine is intended to cure liver cancer (hepatocellular carcinoma) in adult patients.

Q: Does SORANIB cause hair loss?
A: Yes. This medicine may cause hair loss and if this symptom bothers you contact your physician.

Q: Can SORANIB be used in children?
A: No. This medicine is generally not recommended for use in children. Consult your doctor before taking.

PRODUCT INTRODUCTION

Soranib Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer.

Soranib Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits.

Your doctor will decide what dose is necessary and how often you need to take it.
This will depend on what you are being treated for and may change from time to time.
You should take it exactly as your doctor has advised.

Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. click here : Soranib 200

some common side effects

Fatigue, nausea, loss of appetite, hair loss and diarrhea are some common side effects of this medicine. It might cause high blood pressure, so the doctor may ask you for a regular check-up of blood pressure. You must inform your doctor if you notice severe skin reaction such as skin rash, or any pain, swelling, and redness of your hands and feet.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or high blood pressure. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. click here : Soranib 200

USES OF SORANIB TABLET

• Liver cancer
• Kidney cancer
• Thyroid cancer

BENEFITS OF SORANIB TABLET

In Liver cancer

Liver cancer is the cancer that develops in the cells of the liver called hepatocytes. There may be no symptoms present in the early stages of the cancer but as the disease advances to later stages symptoms such as weight loss, stomach pain, vomiting and yellowed skin. Soranib Tablet kills the cancer cells and prevents further growth and spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and do not drink alcohol or smoke. Alcohol intake or smoking can worsen your condition and hinder your recovery.

In Kidney cancer

Soranib Tablet is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc.
It stops cancer growth and prevents multiplication of cancer cells.

This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.

In Thyroid cancer

Thyroid is a butterfly-shaped gland located at the base of your neck.
Your thyroid produces hormones that regulate your heart rate, blood pressure, body temperature and weight.
Thyroid cancer occurs in the cells of the thyroid and it might not cause any symptoms at first.

Soranib Tablet restricts the oxygen supply of the cancer cells and stops its growth as well as further spread.
It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor.

You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

SIDE EFFECTS OF SORANIB TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Soranib 200

• Fatigue
• Nausea
• Loss of appetite
• Diarrhea
• Abdominal pain
• Hair loss
• Weight loss
• Rash
• Painful blisters on hands and feet

HOW TO USE SORANIB TABLET

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Soranib 200 Tablet is to be taken empty stomach.

HOW SORANIB TABLET WORKS

Soranib 200 Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

SAFETY ADVICE

Alcohol

It is not known whether it is safe to consume alcohol with Soranib 200 Tablet. Please consult your doctor.

Pregnancy

Soranib 200 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

Soranib 200 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

Soranib 200 Tablet does not usually affect your ability to drive.

Kidney

Soranib 200 Tablet is safe to use in patients with kidney disease. No dose adjustment of Soranib 200 Tablet is recommended.
Regular monitoring of blood tests may be advised while you are taking this medicine.

Liver

Soranib 200 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Soranib 200 Tablet may be needed. Please consult your doctor.

WHAT IF YOU FORGET TO TAKE SORANIB TABLET?

If you miss a dose of Soranib 200 Tablet, skip it and continue with your normal schedule. Do not double the dose.