Ticstop 25mg Tablet

Ticstop Tablet 10’s is in a class of medications called vesicular monoamine transporter 2 (VMAT2) inhibitors. Huntington’s disease causes sudden shaky, jerky, irregular muscle movements that cannot be controlled. Ticstop Tablet 10’s reduces the amount of certain chemicals that are overactive in the body, causing these uncontrollable muscle movements.

You can take this Ticstop Tablet 10’s with or without food. Inform your doctor before you stop taking this Ticstop Tablet 10’s as its usage cannot be discontinued suddenly. Do not take this Ticstop Tablet 10’s in larger or smaller amounts than recommended by your doctor. Incase if you forget or miss a dose, do not take up the extra Ticstop Tablet 10’s. If you miss the dose for more than five days in a row, talk to your doctor before restarting again.

The common side effects of the Ticstop Tablet 10’s include difficulty in breathing, swelling of face, lips, tongue or throat, decreased appetite, difficulty speaking, nausea, vomiting, pain or burning upon urination. Report to your doctor if you notice any new or worsening symptoms like trouble sleeping, restlessness, feeling more depressed having self-destruction and suicidal thoughts. Call your doctor immediately if you notice lip-smacking, difficulty swallowing, fast heartbeats, tongue movement, blinking or eye movement.

Ticstop Tablet is used to treat Huntington’s disease, a condition in which nerve cells in the brain breakdown over time, thus deteriorating the person’s physical and mental abilities. It also helps to relieve uncontrollable and jerky movements of the body.

Ticstop Tablet should be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. This medication mustn’t be stopped suddenly without talking to your doctor as it may worsen your symptoms. However, discontinue this medicine immediately if you experience neuroleptic malignant syndrome, characterized by fever, muscle rigidity, and altered consciousness or seizures.

Some common side effects of this medicine include nausea, insomnia(difficulty sleeping), anxiety, fatigue, akathisia (restlessness and inability to stay still), and depression. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.

Uses of Ticstop Tablet 10’s

Chorea (sudden movements that you cannot control) associated with Huntington’s disease.

Medicinal Benefits

Overactive secretion of chemicals like serotonin, nor epinephrine, and dopamine in the brain causes degeneration of nerves due to which you may lose the ability to control your thoughts, emotions, or movements. This Ticstop Tablet 10’s works by reducing the overactivity of these natural substances in the brain that transmits signals between the nerves and in turn, lowers brain signals that trigger involuntary muscle movements.

Directions for Use

Swallow the tablet as a whole with a glass of water or any other non-alcoholic drink before a meal or at the end. Start the dose by taking one pill a day at first and then increase to twice a day a week later.

TICSTOP contain Tetrabenazine which belongs to a group of medicine called monoamine depletors. It is used to treat nervous system disorders and treatment of disease-causing jerky, irregular, uncontrollable movements (hyperkinetic motor disorders with Huntington’s chorea).

Huntington’s disease is an inherited, rare disease that cause the progressive degeneration of nerve cells in the brain. It works by decreasing the amount of monoamines such as dopamine, serotonin, and norepinephrine. These are certain natural substances present in the brain which are involved with nerve and muscle function that helps in controlling body movements.

Always take TICSTOP exactly as your doctor has told you. This medicine must be taken with or without food. It is not recommended for use in children. Do not drive or operate machinery while taking this medicine, since it may cause drowsiness.

Before taking this medicine talk to your doctor if you have any kidney, liver, heart problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine. The most common side effects are drowsiness, depression, parkinson-like syndrome (uncontrollable movements of the hand, arm, leg and head, with higher dose), confusion, anxiety, sleeplessness, trouble sleeping, low blood pressure, dysphagia (difficulty in swallowing), nausea, vomiting, diarrhoea and constipation. Read more:

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ticstop Tablet 10’s

Although not everyone gets them, the possible side effects that you may experience are drowsiness, nausea, vomiting, sleeplessness, constipation, confusion. When taken in higher doses, you may experience depression. Very rarely, you may start to have mental changes such as confusion or hallucinations or develop stiffness in your muscles. If you experience any of the side effects talk to your doctor and seek the required medical help, thereby ensuring the safety of the medicine.

In-Depth Precautions and Warning

Drug Warnings
You may have unusual changes in mood or behavior, trouble sitting still, feel nervous, and irritable. Sit or stand slowly if you feel dizzy. Check the progress of Ticstop Tablet 10’s at regular doctor visits and keep track of the symptoms and side effects if noticed any. It may make some people severely depressed and increase the risks of suicidal thoughts and tendencies. Do not take these medicines together with other medications such as resperine and MAO inhibitors. Do not use if you are severely depressed and is on current treatment with antidepressants.

Drug Interactions

Drug-Drug Interaction: Care should be exercised when Ticstop Tablet 10’s is administered in combination with MAO inhibitors (isocarboxazid, linezolid, rasagiline, selegiline, methylene blue injection), antipsychotic medicine or mental/mood conditions (quetiapine, olanzapine, escitalopram, haloperidol, clozapine), to avoid serious drug interactions.

Drug-Food Interaction: Alcohol can increase the nervous system side effects of Ticstop Tablet 10’s such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with Ticstop Tablet 10’s.

Drug-Disease Interaction: People affected with arrhythmias (an irregular heartbeat), depression, liver, kidney diseases, and Huntington disease (an inherited condition in which nerve cells in the brain break down over time) should not take this Ticstop Tablet 10’s.

HOW TO MANAGE SIDE EFFECTS

Nausea and vomiting:

Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Diarrhoea:

Drink lot of fluid such as water or squash, to avoid dehydration. Do not take any other medicines without speaking to a doctor.

Constipation:

Eat fibre rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

SAFETY ADVICE

Alcohol

Ticstop Tablet may cause excessive drowsiness with alcohol.

Pregnancy

Ticstop Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

Ticstop Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

Ticstop Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

There is limited information available on the use of Ticstop Tablet in patients with kidney disease. Please consult your doctor.
However, caution is advised in these patients.

FAQs

Q. Can Ticstop Tablet be crushed?
No, Ticstop Tablet should not be crushed, cut, or chewed. It needs to be swallowed as a whole. But if you cannot swallow the whole tablet, tell your doctor who will probably prescribe you another medicine.

Q. Is Ticstop Tablet an antipsychotic?
Ticstop Tablet is not an antipsychotic. It belongs to the vesicular monoamine transporter 2 (VMAT2) inhibitor class of medicines. It works by changing the activity of some natural substances in the brain that affect muscles and nerves.

Q. What is the most important information that I should know about Ticstop Tablet?
Ticstop Tablet may increase the risk of depression or suicidal thoughts in patients with Huntington’s disease. Huntington’s disease is an inherited disease that causes the progressive breakdown of nerve cells in the brain. Therefore, you should not take Ticstop Tablet if you have Huntington’s disease along with depression.

Q. What should I avoid while taking Ticstop Tablet?
Sleepiness is a common side effect of Ticstop Tablet. Therefore, you should avoid driving or operating heavy machinery if you feel sleepy while taking Ticstop Tablet.

INTERACTIONS

Talk to your doctor if you are taking,

• Reserpine (used to control high blood pressure and treat psychotic states)
• MAO inhibitors (used to treat depression)
• Levodopa (used to treat parkinson’s disease)
• Certain types of antidepressants, opioids, beta-blockers, antihypertensive drug (used to treat high blood pressure)
• Hypnotics and neuroleptics (used to treat psychotic disorders)
• Fluoxetine, paroxetine, terbinafine, moclobemide and quinidine
• Antibiotic such as gatifloxacin, moxifloxacin (used to treat infection)
• Quinidine, procainamide, amiodarone, sotalol (used to treat heart rhythm problems)