ERLOTERO 150MG contains Erlotinib which belongs to the group of medicines called Cytostatic agents. It is used to treat advanced non-small cell lung cancer in adult patients.
It can also be used to treat advanced, unresectable metastatic pancreatic cancer in adult patients in combination with gemcitabine.
It can be prescribed to you either as an initial therapy or as an alternative therapy if your disease remains largely unchanged after initial chemotherapy, provided your cancer cells have specific EGFR mutations.
Erlotinib works by inhibiting the activity of a protein called epidermal growth factor receptor (EGFR), which is known to be responsible for the growth and spread of cancer cells.
Avoid smoking while taking this medicine, because smoking could decrease the amount of the medicine in your blood.
Always take this medicine at least 1 hour before or 2 hours after meals. Avoid concomitant treatment of this medicine with statins because it may increase the risk of muscle pain, tenderness or cramps. Before taking this medicine, inform your doctor if you are pregnant or breastfeeding.
The most common side effect of taking this medicine are skin rash, nausea, vomiting, stomach pain, depression, headache, weight loss and hair loss.
Contact your doctor immediately if any of the above symptom worsens.
ERLOTERO 150MG is not recommended for use in patients with severe liver or kidney disease and in children or adolescents under 18 years of age. Consult your doctor before taking.
USES OF ERLOTERO 150MG:
Treats advanced non-small cell lung cancer in adults
Treats advanced, unrespectable metastatic pancreatic cancer in adult patients in combination with gemcitabine
HOW ERLOTERO 150MG WORKS:
Following oral administration, erlotinib binds to the intracellular portion (tyrosine kinase) of epidermal growth factor receptor (EGFR) and inhibits its activity. EGFR is expressed on the surface of both normal as well as cancer cells. Inhibition of EGFR and it’s signaling significantly decreases tumor proliferation and survival, resulting in cell death. click here : Erlotero 150
DIRECTIONS FOR USE:
Take ERLOTERO 150MG as directed by your physician. It must be taken at least 1 hour before or 2 hours after meals. Do not take this medicine with meals.
Swallow the medicine as whole with a sip of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose for you depending upon your condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.
SIDE EFFECTS OF ERLOTERO 150MG:
Persistent diarrhea and vomiting
Eye irritation due to keratitis or conjunctivitis
Interstitial lung disease (a form of lung irritation)
Sudden difficulty in breathing with cough or fever
Severe abdominal pain
Skin rash in sun exposed areas
Loss of appetite, nausea, stomach pain, indigestion and flatulence
Numbness in extremities
Infection, difficulty in breathing, cough
Acne, itching, dry or cracked skin
Tiredness, fever, rigors
Bleeding from the nose
Inflammatory reactions around fingernail
Infection of hair follicles or hair loss
Flushed or painful palms or soles
HOW TO MANAGE SIDE EFFECTS
Try to rest and relax. Stick to simple meals. Do not eat rich or spicy food.
Eat smaller and frequent meals. Eat and drink slowly, and exercise regularly. If the symptoms get worse, contact your doctor immediately.
Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.
Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.
Avoid hot showers because hot water can irritate the skin. Do not rub or scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use moisturizers to soothe and hydrate the affected area. If it does not get better, speak to a doctor.
Talk to your doctor, if you are taking,
Medicines used to treat bacterial infections (e.g. erythromycin, ciprofloxacin, clarithromycin)
Medicines used to treat epilepsy (e.g. phenytoin, carbamazepine)
Medicines used to treat fits or induce sleep (e.g. phenobarbital, pentobarbital)
Medicines used to reduce stomach acid (e.g. omeprazole or ranitidine)
Medicines used to prevent blood clot (e.g. warfarin)
Protease inhibitors (used to treat HIV infection) such as atazanavir, saquinavir, darunavir
Proteasome inhibitors (used to treat multiple myeloma) such as bortezomib or carfilzomib
Statins (used to reduce high blood cholesterol) such as atorvastatin, rosuvastatin, simvastatin
Antifungals (used to treat fungal infection) e.g. ketoconazole
Rifampicin (used to treat tuberculosis)
St. John?s Wort (a herbal medicine used to treat depression)
Drug : Erlotinib
Pharmacological Category : Cytostatic agent, EGFR tyrosine kinase inhibitor
Therapeutic Indication : Advanced non-small cell lung cancer, Pancreatic cancer
Dosage Forms : Tablet
Store below 20-25°C and keep out of reach of children.
FAQ’s ABOUT ERLOTERO 150MG:
Q: How to take ERLOTERO 150MG?
A: Always take this medicine at least 1 hour before or 2 hours after meals. Swallow the medicine as whole with a sip of water. Do not crush or chew the medicine. Your doctor will decide the correct dose for you depending upon your condition.
Q: Can I smoke while taking ERLOTERO 150MG?
A: No. Avoid smoking while taking this medicine, because smoking could decrease the amount of the medicine in your blood.
Q: Can we take statins while taking ERLOTERO 150MG?
A: No. Avoid concomitant treatment of this medicine with statins because it may increase the risk of muscle pain, tenderness or cramps.
Erlotero 150 mg Tablet should be taken on an empty stomach or should be taken one hour before or 2 hour after meal.
You should continue to take it as long as your doctor advises it. The duration of treatment varies according to your needs and response to treatment. You should take it exactly as your doctor has advised.
Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
most common side effects
It makes you sensitive towards sunlight, hence wear protective clothing or use sunscreen while going out. In case you develop ulceration in mouth, changes in your vision, or breathing difficulties than it is better to inform the doctor.
Your doctor may advise for regular monitoring of liver function while you are taking this medicine.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.
This medicine is not recommended during pregnancy or while breastfeeding.
It is advised to quit smoking while taking this medicine as it can affect the working of the medicine.
If you have to take an antacid or any other medicine, take it at a gap of at least 2 hours after taking the cancer medicine.
USES OF ERLOTERO TABLET
- Non-small cell lung cancer
- Pancreatic cancer
BENEFITS OF ERLOTERO TABLET
In Non-small cell lung cancer
It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor.
You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Pancreatic cancer
This medicine will help to control pancreatic cancer, and will relieve the symptoms such as, lack of appetite or unexplained weight loss.
Erlotero 150mg Tablet helps to stop the action of those chemicals that aid in pancreatic cancer growth and spread. It will help you live a longer and healthier life.
SIDE EFFECTS OF ERLOTERO TABLET
Common side effects of Erlotero
- Abdominal pain
- Bone pain
- Muscle pain
- Stomatitis (Inflammation of the mouth)
- Weight loss
HOW TO USE ERLOTERO TABLET
HOW ERLOTERO TABLET WORKS
Use of this medicine is not advised in patients with severe kidney disease.
Limited information is available on the use of Erlotero 150mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.