Imatib 400 mg Tablet

IMATIB contains Imatinib mesylate which belongs to a group of medicines called corticosteroids which reduces infl?ammation. It is indicated to treat chronic myeloid leukaemia and Philadelphia chromosome positive acute lymphoblastic leukaemia in adults and children.

Leukaemia is a cancer of white blood cells, the cells usually help the body to fight infection. IMATIB also used to treat myelodysplastic/myeloproliferative diseases, hypereosinophilic syndrome (HES) and/or chronic eosinophilic leukaemia, gastrointestinal stromal tumours and dermatofibrosarcoma protuberans in adults. Tyrosine kinases are proteins which act as chemical messengers that are used by the cancer cells to signal to each other for their growth. This medicine works by blocking this enzyme and stops the cancer cells from growing.

Take this medicine according to the dose and frequency as advised by your doctor. Swallow whole with a large glass of water. It can be taken with food. The common side effects are fluid retention, weight gain. Before taking this medicine tell your doctor if you have kidney, liver or heart problems. It is not recommended during pregnancy and breastfeeding.

USES OF IMATIB:

Chronic myeloid leukaemia
Philadelphia chromosome positive acute lymphoblastic leukaemia
Myelodysplastic/myeloproliferative diseases
Hypereosinophilic syndrome (HES) and/or chronic eosinophilic leukaemia
Gastrointestinal stromal tumours
Dermatofibrosarcoma protuberans

HOW IMATIB WORKS:

IMATIB is a protein-tyrosine kinase inhibitor. Tyrosine kinases are proteins which act as chemical messengers that are used by the cancer cells to signal to each other for their growth. Imatinib mesylate by blocking this enzyme stops the cancer cells from growing.

DIRECTIONS FOR USE:

Take this medicine according to the dose and frequency as advised by your doctor. Swallow whole with a large glass of water. It can be taken with food.

SIDE EFFECTS OF IMATIB 400MG:

COMMON

Rapid weight gain (severe fluid retention)
Fever, severe chills
Sore throat
Mouth ulcers
Unexpected bleeding or bruising

INTERACTIONS:

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following,

Levothyroxine
Paracetamol
Herbal medicines (St. John?s Wort)
Medicines used to prevent the formation of blood clots

SYNOPSIS:

Drug : Imatinib
Pharmacological Category : Antineoplastic Agent, BCR-ABL Tyrosine Kinase Inhibitor
Therapeutic Indication : Leukemia, Gastrointestinal stromal tumors
Dosage Forms : Tablet

MORE INFORMATION:

Store below 20-25°C and keep out of reach of children.

FAQ’s ABOUT IMATIB:

Q: Can use IMATIB during pregnancy?
A: This medicine is not recommended during pregnancy, or if you are planning to get pregnant.

Q: Does IMATIB safe while driving?
A: Do not drive or operate any machines since it may cause dizziness, drowsiness or blurred vision

Q: What causes chronic myeloid leukaemia?
A: It is caused by a genetic change in the stem cells produced by the bone marrow which causes the stem cells to produce too many underdeveloped white blood cells.

PRODUCT INTRODUCTION

Imatib 400 Tablet belongs to the class of medicines known as tyrosine kinase inhibitors. It is used in the treatment of blood cancer (chronic myeloid leukaemia and Acute lymphocytic leukemia) and gastrointestinal stromal tumor.

Imatib 400 Tablet should be taken with food, but better to have it same time every day to get the most benefit. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. click here : Imatib 400

Most common side effects

The most common side effects of this medicine include edema, nausea, vomiting, muscle cramps, musculoskeletal pain, diarrhea, rash, fatigue, and abdominal pain. Let your doctor know if you experience unexpected rapid weight gain. Your doctor may advise for regular monitoring of blood cells and liver function while you are taking this medicine. Do not drive or do anything requiring mental focus if you experience dizziness and blurry vision.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

USES OF IMATIB TABLET

• Blood cancer (Chronic myeloid leukaemia)
• Blood cancer (Acute lymphocytic leukemia)
• Gastrointestinal stromal tumour

BENEFITS OF IMATIB TABLET

In Blood cancer (Chronic myeloid leukaemia)

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body’s ability to fight infection. Imatib 400 Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Blood cancer (Acute lymphocytic leukemia)

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body’s ability to fight infection. Imatib 400 Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Gastrointestinal stromal tumour

A gastrointestinal stromal tumor (GIST) is a type of tumor that occurs most commonly in the stomach or small intestine. The tumors develop into the specialized cells called interstitial cells of Cajal (ICCs). Imatib 400 Tablet helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit.

SIDE EFFECTS OF IMATIB TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Imatib

• Edema (swelling)
• Nausea
• Vomiting
• Muscle cramp
• Musculoskeletal (bone, muscle or joint) pain
• Diarrhea
• Rash
• Fatigue
• Abdominal pain

HOW TO USE IMATIB TABLET

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Imatib 400 Tablet is to be taken with food.

HOW IMATIB TABLET WORKS

Imatib 400 Tablet is an anti-cancer medication. A protein enzyme, bcr-abl tyrosine kinase, responsible for the growth of abnormal proliferation of cancer cells. This medicine inhibits the proliferation and induces apoptosis (planned cell death) in bcr-abl positive cells (cancer cells). This is how it works to stop or slow the spread of cancer.

SAFETY ADVICE

Alcohol

It is not known whether it is safe to consume alcohol with Imatib 400 Tablet. Please consult your doctor.

Pregnancy

Imatib 400 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

Imatib 400 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Lactating women should not breastfeed while using this drug and one month after stopping it.

Driving

Imatib 400 Tablet may cause side effects which could affect your ability to drive.

Kidney

Imatib 400 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Imatib 400 Tablet may be needed. Please consult your doctor.

Liver

Imatib 400 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Imatib 400 Tablet may be needed. Please consult your doctor.

WHAT IF YOU FORGET TO TAKE IMATIB TABLET?

If you miss a dose of Imatib 400 Tablet, skip it and continue with your normal schedule. Do not double the dose.