Endace 160 mg Tablet

ENDACE 160MG contain megestrol which belongs to a group of medicine called progestogens. It is used to treat certain types of cancer known as hormone-dependent cancer (including breast cancer).

Cancer is a disease in which abnormal cell divide uncontrollably and destroy body tissue.

Hormone-dependent cancer is a type of cancer that is dependents on a hormone for growth and/or survival which include breast cancer, which is dependent on estrogens like estradiol.

Hormones are substances produced naturally in the body and they act as chemical messengers and help control the activity of cells and organs.

Hormone therapies interfere with the way hormones are made or formed in the body. Many types of cancer depend on hormones to grow.

ENDACE 160MG may stop the cancer growing by changing this hormone balance in the body and slows down the growth of cancer. It can also act directly on cancer cell so that they cannot grow.

The most common side effects are increase in appetite, weight gain, hot flushes, high blood pressure, constipation, increased blood sugar levels.

Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.

USES OF ENDACE 160MG:

Treat certain types of cancer known as hormone-dependent cancer (include breast cancer)

HOW ENDACE 160MG WORKS:

ENDACE 160MG may stop the cancer growing by changing the hormone balance in the body and slows down the growth of cancer. It can also act directly on cancer cell so that they cannot grow.

DIRECTIONS FOR USE:

Always take ENDACE 160MG exactly as your doctor has told you. This medicine must be taken with or without food and try to take at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine.

SIDE EFFECTS OF ENDACE 160MG:

SERIOUS

Swelling of the face, lips, or tongue, skin rash, difficulty breathing
Blood clot (signs include loss of co-ordination, slurred speech, pains in your groin, pains or numbness in your arm or leg (especially in calf of leg), shortness of breath, weakness, headache, and fainting)

COMMON

Increase in appetite and weight gain (not associated with water retention)
Shortness of breath
Hot flushes
Reddening of the face and neck
High blood pressure
Increased blood sugar levels
Rounded face, sometimes called moon face
Constipation
Swelling of a vein due to a blood clot
Blood clot in the lungs
Temporary increase in the sign and symptom of your disease
Changes in mood
Numbness, pain or tingling in finger or thumb
Heart attack
Hair loss
Diarrhoea, tiredness, feeling weak
Impotence
Passing wind
Needing to urinate more often
Nausea and vomiting
Changes in vaginal bleeding (breakthrough bleeding, spotting)
Build-up of fluid which causes swelling (mainly in the ankles)
Pain
Rash, including hives or nettle rash (urticaria)

HOW TO MANAGE SIDE EFFECTS:

Constipation:

Take fibre rich foods such as fresh fruit, vegetables and cereals and drink plenty of water. Exercise more regularly.

Diarrhoea:

Drink lot of fluid such as water or squash, to avoid dehydration. Do not take any other medicines without talking to a doctor.

Nausea and vomiting:

Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

INTERACTIONS

Tell your doctor about all the medicines you use, including prescription and non-prescription medicines and herbal supplements.

SYNOPSIS

Drug : Megestrol
Pharmacological Category : Antineoplastic Agent, Hormone, Appetite Stimulant, Progestin
Therapeutic Indication : Hormone-dependent cancer (including breast cancer)
Dosage Forms : Tablet

MORE INFORMATION

Store below 20-25?C and keep out of reach of children.

FAQs ABOUT ENDACE 160MG:

Q: Does ENDACE 160MG need to be refrigerated?
A: No, there is no need to refrigerate. However, this medicine should not be stored above 25?C. It should be stored in original packaging to protect from moisture.

Q: Does ENDACE 160MG stop periods?
A: No, it does not stop periods.

Q: Can I take ENDACE 160MG during liver disease?
A: It should be used with caution in patients suffering from liver function impairment or active liver diseases.

PRODUCT INTRODUCTION

USES OF ENDACE TABLET

• Breast cancer
• Endometrial cancer

BENEFITS OF ENDACE TABLET

In Breast cancer

Endace 160 Tablet relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples, or changes in the shape or texture of the breast.

It works by altering the production of those hormones in the body that are essential for the growth and spread of breast cancer.

It may also interact with other hormones or have a direct effect on the cancer to stop its growth.

In Endometrial cancer

Endace 160 Tablet is a synthetic hormone which replicates the effect of a natural female hormone called progesterone.
It relieves the symptoms of endometrial cancer (a type of cancer that develops in the lining of the womb) such as, abnormal vaginal bleeding, lower back pain, pain during sex, etc.It interferes with the production and working of those hormones in the body that are essential for the growth and spread of endometrial cancer.
It may also interact with other hormones or have a direct effect on the cancer to stop its growth.

SIDE EFFECTS OF ENDACE TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Endace

• Increased appetite
• Weight gain
• Hot flashes
• High blood pressure
• Constipation
• Increased glucose level in blood

HOW TO USE ENDACE TABLET

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Endace 160 Tablet may be taken with or without food, but it is better to take it at a fixed time.

HOW ENDACE TABLET WORKS

Endace 160 Tablet is a progestin (female hormone). It works in patients with breast cancer and endometrial cancer by affecting female hormones involved in cancer growth. It causes weight gain by increasing appetite.

SAFETY ADVICE

Alcohol

It is not known whether it is safe to consume alcohol with Endace 160 Tablet. Please consult your doctor.

Pregnancy

Endace 160 Tablet is highly unsafe to use during pregnancy. Seek your doctor’s advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

Endace 160 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

Endace 160 Tablet does not usually affect your ability to drive.

Kidney

Endace 160 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Endace 160 Tablet may be needed. Please consult your doctor.

Liver

Endace 160 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Endace 160 Tablet may be needed. Please consult your doctor.