HERDUO 250MG contains Lapatinib which belongs to the group of medicines called antineoplastic agent.
It is used to treat HER2-positive breast cancer which have spread beyond the original tumor or to other organs (advanced or metastatic breast cancer).
HER2-positive breast cancer is a breast cancer that tests positive for a protein called human epidermal growth factor receptor 2 (HER2), which is capable of promoting the growth of cancer cells.
Lapatinib is generally prescribed with other anti-cancer medicine like capecitabine, trastuzumab (for patients with hormone receptor-negative metastatic breast cancer) or aromatase inhibitor (for patients with hormone sensitive metastatic breast cancer). It slows or stops cancer cells from growing or may kill them.
Always take this medicine as directed by your physician. Take this medicine, either at least 1 hour before or 1 hour after food. Prior to the treatment, your doctor will check whether your heart and lungs are working properly or not.
Avoid consumption of alcohol while taking this medicine. Do not drive or operate any machines if your ability is affected by this medicine. Talk to your doctor immediately at the first sign of diarrhea, because it is important that this is treated right away.
Do not take this medicine, if you have diarrhea, liver, kidney or lung problems or are pregnant. The most common side effect of taking this medicine is diarrhea, rash, dry skin, itching, loss of appetite, stomach pain, indigestion, constipation, nausea or vomiting, tiredness, mouth ulcers, trouble in sleeping, pain in hands and feet.
USES OF HERDUO 250MG:
HER2-positive metastatic breast cancer
HOW HERDUO 250MG WORKS:
HERDUO 250MG is an inhibitor of intracellular tyrosine kinase domains of both HER2 and epidermal growth factor receptor (EGFR). It passes through the cell membrane and binds to HER2 and EGFR, found inside the cell. Inhibition of HER2 and EGFR receptors by lapatinib, inhibits the HER2-derived tumor cell growth and division, which in turn reduces tumor cell proliferation.
DIRECTIONS FOR USE:
Always take this medicine as directed by your physician. Take this medicine, either at least 1 hour before or 1 hour after food. Your doctor will decide the correct dose for you depending upon your condition. Swallow the medicine as a whole with a glass of water. Do not crush or chew the medicine. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results. Do not drink grapefruit juice while you are taking HERDUO 250MG.
SIDE EFFECTS OF HERDUO 250MG:
SERIOUS
Diarrhea
COMMON
Rash, dry skin, itching
Loss of appetite, stomach pain, indigestion, constipation
Nausea or vomiting
Tiredness
Mouth ulcers
Trouble in sleeping
Pain in hands and feet
Joint or back pain
Skin reaction on palms of hands or soles of feet (including tingling, numbness, pain, swelling or reddening)
Cough, shortness of breath
Headache
Nose-bleed
Hot flush
Unusual hair loss or thinning
Jaundice (yellow eyes or skin)
Dark urine
Nail infection
HOW TO MANAGE SIDE EFFECTS
Nausea or vomiting:
Try taking this medicine with, or just after a meal or a snack. Stick to simple meals. Do not eat rich or spicy food.
Constipation:
Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.
Diarrhea:
Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.
Stomach pain:
Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.
SYNOPSIS
Drug : Lapatinib
Pharmacological Category : Antineoplastic Agent, HER2-inhibitor, EGFR inhibitor, Tyrosine Kinase Inhibitor
Therapeutic Indication :
HER2-positive metastatic breast cancer
Dosage Forms : Tablet
MORE INFORMATION
Store below 20-25?C and keep out of reach of children.
FAQs ABOUT HERDUO 250MG:
Q: What is the most common side effect of HERDUO 250MG?
A: The most common side effect of this medicine is diarrhoea. Drink lots of fluids, such as water or juice, to avoid dehydration. Consult your doctor immediately if it is severe.
Q: Will HERDUO 250MG cause hair loss?
A: Yes. This medicine may cause unusual hair thinning or loss. Consult your doctor for advice.
Q: Can we take HERDUO 250MG with juice?
A: No. Take this tablet only with water. Avoid drinking juices while taking this medicine, especially grapefruit juice, as it may lead to serious interactions.
PRODUCT INTRODUCTION
Herduo 250 mg Tablet should be taken on an empty stomach or an hour before or 2 hours after a meal. The dose and duration vary according to the severity of your condition and your response to treatment. Take it exactly as prescribed to avoid serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. click here : herduo 250
most common side effects
Before taking Herduo 250 mg Tablet, let your doctor know if you have liver or kidney problems. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are taking. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
USES OF HERDUO TABLET
- Breast cancer
BENEFITS OF HERDUO TABLET
In Breast cancer
SIDE EFFECTS OF HERDUO TABLET
- Abdominal pain
- Back pain
- Breathing problems
- Constipation
- Cough
- Diarrhea
- Fatigue
- Headache
- Hot flashes
- Increased bilirubin in the blood
- Insomnia (difficulty in sleeping)
- Joint pain
- Liver damage
- Loss of appetite
- Mucosal inflammation
- Nausea
- Pain in extremities
- Rash
- Stomatitis (Inflammation of the mouth)
- Vomiting
- Weakness
- Weight gain
HOW TO USE HERDUO TABLET
HOW HERDUO TABLET WORKS
SAFETY ADVICE
Alcohol
Pregnancy
Breast feeding
Driving
Kidney
Limited information is available on the use of Herduo Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Liver
Limited information is available on the use of this medicine in patients with the severe liver disease.
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